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Page 1
Signature active site architectures illuminate the molecular basis for ligand specificity in family 35 carbohydrate binding module.
Correia MA, Abbott DW, Gloster TM, Fernandes VO, Prates JA, Montanier C, Dumon C, Williamson MP, Tunnicliffe RB, Liu Z, Flint JE, Davies GJ, Henrissat B, Coutinho PM, Fontes CM, Gilbert HJ. Correia MA, et al. Among authors: flint je. Biochemistry. 2010 Jul 27;49(29):6193-205. doi: 10.1021/bi1006139. Biochemistry. 2010. PMID: 20496884
A novel, noncatalytic carbohydrate-binding module displays specificity for galactose-containing polysaccharides through calcium-mediated oligomerization.
Montanier CY, Correia MA, Flint JE, Zhu Y, Baslé A, McKee LS, Prates JA, Polizzi SJ, Coutinho PM, Lewis RJ, Henrissat B, Fontes CM, Gilbert HJ. Montanier CY, et al. Among authors: flint je. J Biol Chem. 2011 Jun 24;286(25):22499-509. doi: 10.1074/jbc.M110.217372. Epub 2011 Mar 21. J Biol Chem. 2011. PMID: 21454512 Free PMC article.
Evidence that family 35 carbohydrate binding modules display conserved specificity but divergent function.
Montanier C, van Bueren AL, Dumon C, Flint JE, Correia MA, Prates JA, Firbank SJ, Lewis RJ, Grondin GG, Ghinet MG, Gloster TM, Herve C, Knox JP, Talbot BG, Turkenburg JP, Kerovuo J, Brzezinski R, Fontes CM, Davies GJ, Boraston AB, Gilbert HJ. Montanier C, et al. Among authors: flint je. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3065-70. doi: 10.1073/pnas.0808972106. Epub 2009 Feb 13. Proc Natl Acad Sci U S A. 2009. PMID: 19218457 Free PMC article.
Understanding how diverse beta-mannanases recognize heterogeneous substrates.
Tailford LE, Ducros VM, Flint JE, Roberts SM, Morland C, Zechel DL, Smith N, Bjørnvad ME, Borchert TV, Wilson KS, Davies GJ, Gilbert HJ. Tailford LE, et al. Among authors: flint je. Biochemistry. 2009 Jul 28;48(29):7009-18. doi: 10.1021/bi900515d. Biochemistry. 2009. PMID: 19441796
The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions.
Montanier C, Money VA, Pires VM, Flint JE, Pinheiro BA, Goyal A, Prates JA, Izumi A, Stålbrand H, Morland C, Cartmell A, Kolenova K, Topakas E, Dodson EJ, Bolam DN, Davies GJ, Fontes CM, Gilbert HJ. Montanier C, et al. Among authors: flint je. PLoS Biol. 2009 Mar 31;7(3):e71. doi: 10.1371/journal.pbio.1000071. PLoS Biol. 2009. PMID: 19338387 Free PMC article.
26 results