Kholodenko BN - Search Results

1

Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics.

Nakakuki T, Birtwistle MR, Saeki Y, Yumoto N, Ide K, Nagashima T, Brusch L, Ogunnaike BA, Okada-Hatakeyama M, Kholodenko BN. Nakakuki T, et al. Among authors: kholodenko bn. Cell. 2010 May 28;141(5):884-96. doi: 10.1016/j.cell.2010.03.054. Epub 2010 May 20. Cell. 2010. PMID: 20493519 Free PMC article.

2

Quantifying gene network connectivity in silico: scalability and accuracy of a modular approach.

Yalamanchili N, Zak DE, Ogunnaike BA, Schwaber JS, Kriete A, Kholodenko BN. Yalamanchili N, et al. Among authors: kholodenko bn. Syst Biol (Stevenage). 2006 Jul;153(4):236-46. doi: 10.1049/ip-syb:20050090. Syst Biol (Stevenage). 2006. PMID: 16986625 Free PMC article.

3

Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.

Birtwistle MR, Hatakeyama M, Yumoto N, Ogunnaike BA, Hoek JB, Kholodenko BN. Birtwistle MR, et al. Among authors: kholodenko bn. Mol Syst Biol. 2007;3:144. doi: 10.1038/msb4100188. Epub 2007 Nov 13. Mol Syst Biol. 2007. PMID: 18004277 Free PMC article.

4

Endocytosis and signalling: a meeting with mathematics.

Birtwistle MR, Kholodenko BN. Birtwistle MR, et al. Among authors: kholodenko bn. Mol Oncol. 2009 Aug;3(4):308-20. doi: 10.1016/j.molonc.2009.05.009. Epub 2009 Jun 16. Mol Oncol. 2009. PMID: 19596615 Free PMC article. Review.

5

Four-dimensional dynamics of MAPK information processing systems.

Kholodenko BN, Birtwistle MR. Kholodenko BN, et al. Wiley Interdiscip Rev Syst Biol Med. 2009 Jul-Aug;1(1):28-44. doi: 10.1002/wsbm.16. Wiley Interdiscip Rev Syst Biol Med. 2009. PMID: 20182652 Free PMC article. Review.

6

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier.

Sturm OE, Orton R, Grindlay J, Birtwistle M, Vyshemirsky V, Gilbert D, Calder M, Pitt A, Kholodenko B, Kolch W. Sturm OE, et al. Sci Signal. 2010 Dec 21;3(153):ra90. doi: 10.1126/scisignal.2001212. Sci Signal. 2010. PMID: 21177493

7

Catching transcriptional regulation by thermostatistical modeling.

Frank TD, Cheong A, Okada-Hatakeyama M, Kholodenko BN. Frank TD, et al. Among authors: kholodenko bn. Phys Biol. 2012 Aug;9(4):045007. doi: 10.1088/1478-3975/9/4/045007. Epub 2012 Aug 7. Phys Biol. 2012. PMID: 22871947

8

Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise.

Birtwistle MR, Rauch J, Kiyatkin A, Aksamitiene E, Dobrzyński M, Hoek JB, Kolch W, Ogunnaike BA, Kholodenko BN. Birtwistle MR, et al. Among authors: kholodenko bn. BMC Syst Biol. 2012 Aug 24;6:109. doi: 10.1186/1752-0509-6-109. BMC Syst Biol. 2012. PMID: 22920937 Free PMC article.

9

Mammalian protein expression noise: scaling principles and the implications for knockdown experiments.

Birtwistle MR, von Kriegsheim A, Dobrzyński M, Kholodenko BN, Kolch W. Birtwistle MR, et al. Among authors: kholodenko bn. Mol Biosyst. 2012 Nov;8(11):3068-76. doi: 10.1039/c2mb25168j. Mol Biosyst. 2012. PMID: 22990612

10

A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.

Nguyen LK, Cavadas MA, Scholz CC, Fitzpatrick SF, Bruning U, Cummins EP, Tambuwala MM, Manresa MC, Kholodenko BN, Taylor CT, Cheong A. Nguyen LK, et al. Among authors: kholodenko bn. J Cell Sci. 2013 Mar 15;126(Pt 6):1454-63. doi: 10.1242/jcs.119974. Epub 2013 Feb 6. J Cell Sci. 2013. PMID: 23390316

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