Deguchi J - Search Results

1

Comparison of potential risks of lactic acidosis induction by biguanides in rats.

Bando K, Ochiai S, Kunimatsu T, Deguchi J, Kimura J, Funabashi H, Seki T. Bando K, et al. Among authors: deguchi j. Regul Toxicol Pharmacol. 2010 Oct;58(1):155-60. doi: 10.1016/j.yrtph.2010.05.005. Epub 2010 May 19. Regul Toxicol Pharmacol. 2010. PMID: 20488215

2

Improvement of the embryonic stem cell test endpoint analysis by use of field potential detection.

Koseki N, Deguchi J, Yamada T, Funabashi H, Seki T. Koseki N, et al. Among authors: deguchi j. J Toxicol Sci. 2010 Oct;35(5):619-29. doi: 10.2131/jts.35.619. J Toxicol Sci. 2010. PMID: 20930457 Free article.

3

Usefulness of field potential as a marker of embryonic stem cell-derived cardiomyocytes, and endpoint analysis of embryonic stem cell test.

Koseki N, Deguchi J, Yamada T, Funabashi H, Seki T. Koseki N, et al. Among authors: deguchi j. J Toxicol Sci. 2010 Dec;35(6):899-909. doi: 10.2131/jts.35.899. J Toxicol Sci. 2010. PMID: 21139340 Free article.

4

Usefulness of cardiotoxicity assessment using calcium transient in human induced pluripotent stem cell-derived cardiomyocytes.

Watanabe H, Honda Y, Deguchi J, Yamada T, Bando K. Watanabe H, et al. Among authors: deguchi j. J Toxicol Sci. 2017;42(4):519-527. doi: 10.2131/jts.42.519. J Toxicol Sci. 2017. PMID: 28717111 Free article.

5

Improvement of the evaluation method for teratogenicity using zebrafish embryos.

Yamashita A, Inada H, Chihara K, Yamada T, Deguchi J, Funabashi H. Yamashita A, et al. Among authors: deguchi j. J Toxicol Sci. 2014 Jun;39(3):453-64. doi: 10.2131/jts.39.453. J Toxicol Sci. 2014. PMID: 24849680 Free article.

6

Hepatotoxicants induce cytokine imbalance in response to innate immune system.

Goto S, Deguchi J, Nishio N, Nomura N, Funabashi H. Goto S, et al. Among authors: deguchi j. J Toxicol Sci. 2015 Jun;40(3):389-404. doi: 10.2131/jts.40.389. J Toxicol Sci. 2015. PMID: 25972199 Free article.

7

Establishment of a novel experimental protocol for drug-induced seizure liability screening based on a locomotor activity assay in zebrafish.

Koseki N, Deguchi J, Yamashita A, Miyawaki I, Funabashi H. Koseki N, et al. Among authors: deguchi j. J Toxicol Sci. 2014 Aug;39(4):579-600. doi: 10.2131/jts.39.579. J Toxicol Sci. 2014. PMID: 25056783 Free article.

8

Troglitazone Inhibits Bile Acid Amidation: A Possible Risk Factor for Liver Injury.

Ogimura E, Nakagawa T, Deguchi J, Sekine S, Ito K, Bando K. Ogimura E, et al. Among authors: deguchi j. Toxicol Sci. 2017 Aug 1;158(2):347-355. doi: 10.1093/toxsci/kfx091. Toxicol Sci. 2017. PMID: 28486596

9

2-({6-[(3R)-3-amino-3-methylpiperidine-1-yl]-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5H-pyrrolo[3,2-d]pyrimidine-5-yl}methyl)-4-fluorobenzonitrile (DSR-12727): a potent, orally active dipeptidyl peptidase IV inhibitor without mechanism-based inactivation of CYP3A.

Nishio Y, Kimura H, Sawada N, Sugaru E, Horiguchi M, Ono M, Furuta Y, Sakai M, Masui Y, Otani M, Hashizuka T, Honda Y, Deguchi J, Nakagawa T, Nakahira H. Nishio Y, et al. Among authors: deguchi j. Bioorg Med Chem. 2011 Sep 15;19(18):5490-9. doi: 10.1016/j.bmc.2011.07.042. Epub 2011 Aug 4. Bioorg Med Chem. 2011. PMID: 21865048

10

Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish.

Yamashita A, Deguchi J, Honda Y, Yamada T, Miyawaki I, Nishimura Y, Tanaka T. Yamashita A, et al. Among authors: deguchi j. J Pharmacol Toxicol Methods. 2019 Mar-Apr;96:34-45. doi: 10.1016/j.vascn.2018.12.006. Epub 2018 Dec 27. J Pharmacol Toxicol Methods. 2019. PMID: 30594530

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