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Synaptotagmin-mediated vesicle fusion regulates cell migration.
Colvin RA, Means TK, Diefenbach TJ, Moita LF, Friday RP, Sever S, Campanella GS, Abrazinski T, Manice LA, Moita C, Andrews NW, Wu D, Hacohen N, Luster AD. Colvin RA, et al. Among authors: sever s. Nat Immunol. 2010 Jun;11(6):495-502. doi: 10.1038/ni.1878. Epub 2010 May 16. Nat Immunol. 2010. PMID: 20473299 Free PMC article.
The small GTPase regulatory protein Rac1 drives podocyte injury independent of cationic channel protein TRPC5.
Polat OK, Isaeva E, Sudhini YR, Knott B, Zhu K, Noben M, Suresh Kumar V, Endlich N, Mangos S, Reddy TV, Samelko B, Wei C, Altintas MM, Dryer SE, Sever S, Staruschenko A, Reiser J. Polat OK, et al. Among authors: sever s. Kidney Int. 2023 Jun;103(6):1056-1062. doi: 10.1016/j.kint.2023.01.016. Epub 2023 Feb 5. Kidney Int. 2023. PMID: 36750145 Free PMC article.
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Hahm E, Wei C, Fernandez I, Li J, Tardi NJ, Tracy M, Wadhwani S, Cao Y, Peev V, Zloza A, Lusciks J, Hayek SS, O'Connor C, Bitzer M, Gupta V, Sever S, Sykes DB, Scadden DT, Reiser J. Hahm E, et al. Among authors: sever s. Nat Med. 2017 Jan;23(1):100-106. doi: 10.1038/nm.4242. Epub 2016 Dec 12. Nat Med. 2017. PMID: 27941791 Free PMC article.
A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.
Hayek SS, Koh KH, Grams ME, Wei C, Ko YA, Li J, Samelko B, Lee H, Dande RR, Lee HW, Hahm E, Peev V, Tracy M, Tardi NJ, Gupta V, Altintas MM, Garborcauskas G, Stojanovic N, Winkler CA, Lipkowitz MS, Tin A, Inker LA, Levey AS, Zeier M, Freedman BI, Kopp JB, Skorecki K, Coresh J, Quyyumi AA, Sever S, Reiser J. Hayek SS, et al. Among authors: sever s. Nat Med. 2017 Aug;23(8):945-953. doi: 10.1038/nm.4362. Epub 2017 Jun 26. Nat Med. 2017. PMID: 28650456 Free PMC article.
Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury.
Mukherjee K, Gu C, Collins A, Mettlen M, Samelko B, Altintas MM, Sudhini YR, Wang X, Bouley R, Brown D, Pedro BP, Bane SL, Gupta V, Brinkkoetter PT, Hagmann H, Reiser J, Sever S. Mukherjee K, et al. Among authors: sever s. Nat Commun. 2022 May 3;13(1):2422. doi: 10.1038/s41467-022-30101-4. Nat Commun. 2022. PMID: 35504916 Free PMC article.
Dynamin and endocytosis.
Sever S. Sever S. Curr Opin Cell Biol. 2002 Aug;14(4):463-7. doi: 10.1016/s0955-0674(02)00347-2. Curr Opin Cell Biol. 2002. PMID: 12383797 Review.
AP-2 makes room for rivals.
Sever S. Sever S. Dev Cell. 2003 Oct;5(4):530-2. doi: 10.1016/s1534-5807(03)00304-6. Dev Cell. 2003. PMID: 14536052 Free article.
74 results