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Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.
Landeira D, Sauer S, Poot R, Dvorkina M, Mazzarella L, Jørgensen HF, Pereira CF, Leleu M, Piccolo FM, Spivakov M, Brookes E, Pombo A, Fisher C, Skarnes WC, Snoek T, Bezstarosti K, Demmers J, Klose RJ, Casanova M, Tavares L, Brockdorff N, Merkenschlager M, Fisher AG. Landeira D, et al. Among authors: mazzarella l. Nat Cell Biol. 2010 Jun;12(6):618-24. doi: 10.1038/ncb2065. Epub 2010 May 16. Nat Cell Biol. 2010. PMID: 20473294 Free PMC article.
Early chromatin unfolding by RUNX1: a molecular explanation for differential requirements during specification versus maintenance of the hematopoietic gene expression program.
Hoogenkamp M, Lichtinger M, Krysinska H, Lancrin C, Clarke D, Williamson A, Mazzarella L, Ingram R, Jorgensen H, Fisher A, Tenen DG, Kouskoff V, Lacaud G, Bonifer C. Hoogenkamp M, et al. Among authors: mazzarella l. Blood. 2009 Jul 9;114(2):299-309. doi: 10.1182/blood-2008-11-191890. Epub 2009 Apr 1. Blood. 2009. PMID: 19339695 Free PMC article.
Runx proteins regulate Foxp3 expression.
Bruno L, Mazzarella L, Hoogenkamp M, Hertweck A, Cobb BS, Sauer S, Hadjur S, Leleu M, Naoe Y, Telfer JC, Bonifer C, Taniuchi I, Fisher AG, Merkenschlager M. Bruno L, et al. Among authors: mazzarella l. J Exp Med. 2009 Oct 26;206(11):2329-37. doi: 10.1084/jem.20090226. Epub 2009 Oct 19. J Exp Med. 2009. PMID: 19841090 Free PMC article.
Increased BMI correlates with higher risk of disease relapse and differentiation syndrome in patients with acute promyelocytic leukemia treated with the AIDA protocols.
Breccia M, Mazzarella L, Bagnardi V, Disalvatore D, Loglisci G, Cimino G, Testi AM, Avvisati G, Petti MC, Minotti C, Latagliata R, Foà R, Pelicci PG, Lo-Coco F. Breccia M, et al. Among authors: mazzarella l. Blood. 2012 Jan 5;119(1):49-54. doi: 10.1182/blood-2011-07-369595. Epub 2011 Nov 2. Blood. 2012. PMID: 22049518 Free article.
Caloric restriction leads to druggable LSD1-dependent cancer stem cells expansion.
Pallavi R, Gatti E, Durfort T, Stendardo M, Ravasio R, Leonardi T, Falvo P, Duso BA, Punzi S, Xieraili A, Polazzi A, Verrelli D, Trastulli D, Ronzoni S, Frascolla S, Perticari G, Elgendy M, Varasi M, Colombo E, Giorgio M, Lanfrancone L, Minucci S, Mazzarella L, Pelicci PG. Pallavi R, et al. Among authors: mazzarella l. Nat Commun. 2024 Jan 27;15(1):828. doi: 10.1038/s41467-023-44348-y. Nat Commun. 2024. PMID: 38280853 Free PMC article.
The genomic and epigenomic landscapes of AML.
Mazzarella L, Riva L, Luzi L, Ronchini C, Pelicci PG. Mazzarella L, et al. Semin Hematol. 2014 Oct;51(4):259-72. doi: 10.1053/j.seminhematol.2014.08.007. Epub 2014 Aug 26. Semin Hematol. 2014. PMID: 25311739
243 results