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First-in-Human Study of 23ME-00610, an Antagonistic Antibody for Genetically Validated CD200R1 Immune Checkpoint, in Participants with Advanced Solid Malignancies.
Kummar S, Razak AA, Laurie S, Glatt DM, Kell S, Diep AN, Schmidt M, Hom C, German C, Shringarpure SS, Majeed SR, Rasco D. Kummar S, et al. Among authors: hom c. Cancer Res Commun. 2025 Jan 1;5(1):94-105. doi: 10.1158/2767-9764.CRC-24-0568. Cancer Res Commun. 2025. PMID: 39651931 Free PMC article. Clinical Trial.
Timeline to symptomatic Alzheimer's disease in people with Down syndrome as assessed by amyloid-PET and tau-PET: a longitudinal cohort study.
Schworer EK, Zammit MD, Wang J, Handen BL, Betthauser T, Laymon CM, Tudorascu DL, Cohen AD, Zaman SH, Ances BM, Mapstone M, Head E, Christian BT, Hartley SL; Alzheimer's Biomarker Consortium–Down Syndrome (ABC–DS). Schworer EK, et al. Lancet Neurol. 2024 Dec;23(12):1214-1224. doi: 10.1016/S1474-4422(24)00426-5. Lancet Neurol. 2024. PMID: 39577922
The effects of mosaicism on biological and clinical markers of Alzheimer's disease in adults with Down syndrome.
Xicota L, Dang LT, Lee A, Krinsky-McHale S, Pang D, Melilli L, O'Bryant S, Henson RL, Laymon C, Lai F, Rosas HD, Ances B, Lott I, Hom C, Christian B, Hartley S, Zaman S, Head E, Mapstone M, Jin Z, Silverman W, Schupf N, Handen B, Lee JH; Alzheimer's Biomarker Consortium – Down Syndrome (ABC-DS). Xicota L, et al. Among authors: hom c. EBioMedicine. 2024 Dec;110:105433. doi: 10.1016/j.ebiom.2024.105433. Epub 2024 Nov 4. EBioMedicine. 2024. PMID: 39500037 Free PMC article.
Cerebrovascular disease is associated with Alzheimer's plasma biomarker concentrations in adults with Down syndrome.
Edwards NC, Lao PJ, Alshikho MJ, Ericsson OM, Rizvi B, Petersen ME, O'Bryant S, Aguilar LF, Simoes S, Mapstone M, Tudorascu DL, Janelidze S, Hansson O, Handen BL, Christian BT, Lee JH, Lai F, Rosas HD, Zaman S, Lott IT, Yassa MA; Alzheimer’s Biomarkers Consortium–Down Syndrome (ABC-DS) Investigators; Gutierrez J, Wilcock DM, Head E, Brickman AM. Edwards NC, et al. Brain Commun. 2024 Sep 25;6(5):fcae331. doi: 10.1093/braincomms/fcae331. eCollection 2024. Brain Commun. 2024. PMID: 39403075 Free PMC article.
His brain is on FIRES.
Liverant Y, Delport C, Henle I, Hom C, Wolf S, McGoldrick P, Overby P, Gulko E, Hirschberger R. Liverant Y, et al. Among authors: hom c. J Neurol. 2024 Sep;271(9):6382-6387. doi: 10.1007/s00415-024-12539-2. Epub 2024 Jul 21. J Neurol. 2024. PMID: 39033467 No abstract available.
A Neuropathology Case Report of a Woman with Down Syndrome who Remained Cognitively Stable.
Liou JJ, Lou J, Nakagiri J, Yong W, Hom CL, Doran EW, Totoiu M, Lott I, Mapstone M, Keator DB, Brickman AM, Wright S, Nelson B, Lai F, Xicota L, Dang LT, Li J, Santini T, Mettenburg JM, Ikonomovic MD, Kofler J, Ibrahim T, Head E; Alzheimer Biomarker Consortium - Down Syndrome. Liou JJ, et al. Among authors: hom cl. medRxiv [Preprint]. 2024 Jun 3:2024.06.01.24308050. doi: 10.1101/2024.06.01.24308050. medRxiv. 2024. PMID: 38883742 Free PMC article. Preprint.
A pathway linking pulse pressure to dementia in adults with Down syndrome.
Rizvi B, Lao PJ, Sathishkumar M, Taylor L, Queder N, McMillan L, Edwards NC, Keator DB, Doran E, Hom C, Nguyen D, Rosas HD, Lai F, Schupf N, Gutierrez J, Silverman W, Lott IT, Mapstone M, Wilcock DM, Head E, Yassa MA, Brickman AM. Rizvi B, et al. Among authors: hom c. Brain Commun. 2024 May 9;6(3):fcae157. doi: 10.1093/braincomms/fcae157. eCollection 2024. Brain Commun. 2024. PMID: 38764776 Free PMC article.
69 results