Aladjem MI - Search Results

1

Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damage.

Conti C, Leo E, Eichler GS, Sordet O, Martin MM, Fan A, Aladjem MI, Pommier Y. Conti C, et al. Among authors: aladjem mi. Cancer Res. 2010 Jun 1;70(11):4470-80. doi: 10.1158/0008-5472.CAN-09-3028. Epub 2010 May 11. Cancer Res. 2010. PMID: 20460513 Free PMC article.

2

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes.

Furuta T, Takemura H, Liao ZY, Aune GJ, Redon C, Sedelnikova OA, Pilch DR, Rogakou EP, Celeste A, Chen HT, Nussenzweig A, Aladjem MI, Bonner WM, Pommier Y. Furuta T, et al. Among authors: aladjem mi. J Biol Chem. 2003 May 30;278(22):20303-12. doi: 10.1074/jbc.M300198200. Epub 2003 Mar 25. J Biol Chem. 2003. PMID: 12660252 Free article.

3

Dynamic alterations of replication timing in mammalian cells.

Lin CM, Fu H, Martinovsky M, Bouhassira E, Aladjem MI. Lin CM, et al. Among authors: aladjem mi. Curr Biol. 2003 Jun 17;13(12):1019-28. doi: 10.1016/s0960-9822(03)00382-8. Curr Biol. 2003. PMID: 12814547 Free article.

4

Molecular interaction maps--a diagrammatic graphical language for bioregulatory networks.

Aladjem MI, Pasa S, Parodi S, Weinstein JN, Pommier Y, Kohn KW. Aladjem MI, et al. Sci STKE. 2004 Feb 24;2004(222):pe8. doi: 10.1126/stke.2222004pe8. Sci STKE. 2004. PMID: 14997004 Review.

5

Molecular interaction maps of bioregulatory networks: a general rubric for systems biology.

Kohn KW, Aladjem MI, Weinstein JN, Pommier Y. Kohn KW, et al. Among authors: aladjem mi. Mol Biol Cell. 2006 Jan;17(1):1-13. doi: 10.1091/mbc.e05-09-0824. Epub 2005 Nov 2. Mol Biol Cell. 2006. PMID: 16267266 Free PMC article.

6

p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine.

Furuta T, Hayward RL, Meng LH, Takemura H, Aune GJ, Bonner WM, Aladjem MI, Kohn KW, Pommier Y. Furuta T, et al. Among authors: aladjem mi. Oncogene. 2006 May 11;25(20):2839-49. doi: 10.1038/sj.onc.1209313. Oncogene. 2006. PMID: 16407843

7

Chk2 molecular interaction map and rationale for Chk2 inhibitors.

Pommier Y, Weinstein JN, Aladjem MI, Kohn KW. Pommier Y, et al. Among authors: aladjem mi. Clin Cancer Res. 2006 May 1;12(9):2657-61. doi: 10.1158/1078-0432.CCR-06-0743. Clin Cancer Res. 2006. PMID: 16675556

8

Depicting combinatorial complexity with the molecular interaction map notation.

Kohn KW, Aladjem MI, Kim S, Weinstein JN, Pommier Y. Kohn KW, et al. Among authors: aladjem mi. Mol Syst Biol. 2006;2:51. doi: 10.1038/msb4100088. Epub 2006 Oct 3. Mol Syst Biol. 2006. PMID: 17016517 Free PMC article. Review.

9

DNA-PK is involved in repairing a transient surge of DNA breaks induced by deceleration of DNA replication.

Shimura T, Martin MM, Torres MJ, Gu C, Pluth JM, DeBernardi MA, McDonald JS, Aladjem MI. Shimura T, et al. Among authors: aladjem mi. J Mol Biol. 2007 Mar 30;367(3):665-80. doi: 10.1016/j.jmb.2007.01.018. Epub 2007 Jan 12. J Mol Biol. 2007. PMID: 17280685 Free PMC article.

10

The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and -DNA fiber analyses.

Seiler JA, Conti C, Syed A, Aladjem MI, Pommier Y. Seiler JA, et al. Among authors: aladjem mi. Mol Cell Biol. 2007 Aug;27(16):5806-18. doi: 10.1128/MCB.02278-06. Epub 2007 May 21. Mol Cell Biol. 2007. PMID: 17515603 Free PMC article.

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