Jha RK - Search Results

1

Computational design of a PAK1 binding protein.

Jha RK, Leaver-Fay A, Yin S, Wu Y, Butterfoss GL, Szyperski T, Dokholyan NV, Kuhlman B. Jha RK, et al. J Mol Biol. 2010 Jul 9;400(2):257-70. doi: 10.1016/j.jmb.2010.05.006. Epub 2010 May 10. J Mol Biol. 2010. PMID: 20460129 Free PMC article.

2

Scaling behavior and structure of denatured proteins.

Ding F, Jha RK, Dokholyan NV. Ding F, et al. Among authors: jha rk. Structure. 2005 Jul;13(7):1047-54. doi: 10.1016/j.str.2005.04.009. Structure. 2005. PMID: 16004876 Free article.

3

Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications.

Jha RK, Wu YI, Zawistowski JS, MacNevin C, Hahn KM, Kuhlman B. Jha RK, et al. J Mol Biol. 2011 Oct 21;413(2):513-22. doi: 10.1016/j.jmb.2011.08.022. Epub 2011 Aug 24. J Mol Biol. 2011. PMID: 21888918 Free PMC article.

4

Combined computational design of a zinc-binding site and a protein-protein interaction: one open zinc coordination site was not a robust hotspot for de novo ubiquitin binding.

Der BS, Jha RK, Lewis SM, Thompson PM, Guntas G, Kuhlman B. Der BS, et al. Among authors: jha rk. Proteins. 2013 Jul;81(7):1245-55. doi: 10.1002/prot.24280. Epub 2013 Apr 20. Proteins. 2013. PMID: 23504819 Free PMC article.

5

Rosetta comparative modeling for library design: Engineering alternative inducer specificity in a transcription factor.

Jha RK, Chakraborti S, Kern TL, Fox DT, Strauss CE. Jha RK, et al. Proteins. 2015 Jul;83(7):1327-40. doi: 10.1002/prot.24828. Epub 2015 May 29. Proteins. 2015. PMID: 25974100

6

A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor.

Jha RK, Kern TL, Kim Y, Tesar C, Jedrzejczak R, Joachimiak A, Strauss CE. Jha RK, et al. Nucleic Acids Res. 2016 Sep 30;44(17):8490-500. doi: 10.1093/nar/gkw687. Epub 2016 Aug 17. Nucleic Acids Res. 2016. PMID: 27536006 Free PMC article.

7

Engineering an Acinetobacter regulon for biosensing and high-throughput enzyme screening in E. coli via flow cytometry.

Jha RK, Kern TL, Fox DT, M Strauss CE. Jha RK, et al. Nucleic Acids Res. 2014 Jul;42(12):8150-60. doi: 10.1093/nar/gku444. Epub 2014 May 26. Nucleic Acids Res. 2014. PMID: 24861620 Free PMC article.

8

Exploring the sequence-function relationship in transcriptional regulation by the lac O1 operator.

Maity TS, Jha RK, Strauss CE, Dunbar J. Maity TS, et al. Among authors: jha rk. FEBS J. 2012 Jul;279(14):2534-43. doi: 10.1111/j.1742-4658.2012.08635.x. Epub 2012 Jun 15. FEBS J. 2012. PMID: 22594825 Free article.

9

3D structure analysis of PAKs: A clue to the rational design for affinity reagents and blockers.

Jha RK, Strauss CE. Jha RK, et al. Cell Logist. 2012 Apr 1;2(2):69-77. doi: 10.4161/cl.21883. Cell Logist. 2012. PMID: 23162739 Free PMC article.

10

An improved Protein G with higher affinity for human/rabbit IgG Fc domains exploiting a computationally designed polar network.

Jha RK, Gaiotto T, Bradbury AR, Strauss CE. Jha RK, et al. Protein Eng Des Sel. 2014 Apr;27(4):127-34. doi: 10.1093/protein/gzu005. Epub 2014 Mar 14. Protein Eng Des Sel. 2014. PMID: 24632761 Free PMC article.

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