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Rac1 is essential for basement membrane-dependent epiblast survival.
He X, Liu J, Qi Y, Brakebusch C, Chrostek-Grashoff A, Edgar D, Yurchenco PD, Corbett SA, Lowry SF, Graham AM, Han Y, Li S. He X, et al. Among authors: brakebusch c. Mol Cell Biol. 2010 Jul;30(14):3569-81. doi: 10.1128/MCB.01366-09. Epub 2010 May 10. Mol Cell Biol. 2010. PMID: 20457815 Free PMC article.
Rac1 is essential for phospholipase C-gamma2 activation in platelets.
Pleines I, Elvers M, Strehl A, Pozgajova M, Varga-Szabo D, May F, Chrostek-Grashoff A, Brakebusch C, Nieswandt B. Pleines I, et al. Among authors: brakebusch c. Pflugers Arch. 2009 Mar;457(5):1173-85. doi: 10.1007/s00424-008-0573-7. Epub 2008 Aug 13. Pflugers Arch. 2009. PMID: 18704487
Rac1 regulates neuronal polarization through the WAVE complex.
Tahirovic S, Hellal F, Neukirchen D, Hindges R, Garvalov BK, Flynn KC, Stradal TE, Chrostek-Grashoff A, Brakebusch C, Bradke F. Tahirovic S, et al. Among authors: brakebusch c. J Neurosci. 2010 May 19;30(20):6930-43. doi: 10.1523/JNEUROSCI.5395-09.2010. J Neurosci. 2010. PMID: 20484635 Free PMC article.
Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1.
Tscharntke M, Pofahl R, Chrostek-Grashoff A, Smyth N, Niessen C, Niemann C, Hartwig B, Herzog V, Klein HW, Krieg T, Brakebusch C, Haase I. Tscharntke M, et al. Among authors: brakebusch c. J Cell Sci. 2007 Apr 15;120(Pt 8):1480-90. doi: 10.1242/jcs.03426. Epub 2007 Mar 27. J Cell Sci. 2007. PMID: 17389689
191 results