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Structures of the PKC-iota kinase domain in its ATP-bound and apo forms reveal defined structures of residues 533-551 in the C-terminal tail and their roles in ATP binding.
Takimura T, Kamata K, Fukasawa K, Ohsawa H, Komatani H, Yoshizumi T, Takahashi I, Kotani H, Iwasawa Y. Takimura T, et al. Among authors: komatani h. Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):577-83. doi: 10.1107/S0907444910005639. Epub 2010 Apr 21. Acta Crystallogr D Biol Crystallogr. 2010. PMID: 20445233
Imidazopyridine derivatives as potent and selective Polo-like kinase (PLK) inhibitors.
Sato Y, Onozaki Y, Sugimoto T, Kurihara H, Kamijo K, Kadowaki C, Tsujino T, Watanabe A, Otsuki S, Mitsuya M, Iida M, Haze K, Machida T, Nakatsuru Y, Komatani H, Kotani H, Iwasawa Y. Sato Y, et al. Among authors: komatani h. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4673-8. doi: 10.1016/j.bmcl.2009.06.084. Epub 2009 Jun 25. Bioorg Med Chem Lett. 2009. PMID: 19589677
Sequence-selective DNA cleavage by a topoisomerase I poison, NB-506.
Fukasawa K, Komatani H, Hara Y, Suda H, Okura A, Nishimura S, Yoshinari T. Fukasawa K, et al. Among authors: komatani h. Int J Cancer. 1998 Jan 5;75(1):145-50. doi: 10.1002/(sici)1097-0215(19980105)75:1<145::aid-ijc22>3.0.co;2-e. Int J Cancer. 1998. PMID: 9426703
[Novel anti-cancer compounds targeting the cell cycle].
Hirai H, Shimomura T, Komatani H, Kotani H. Hirai H, et al. Among authors: komatani h. Nihon Yakurigaku Zasshi. 2009 Jan;133(1):27-31. doi: 10.1254/fpj.133.27. Nihon Yakurigaku Zasshi. 2009. PMID: 19145048 Review. Japanese. No abstract available.
24 results