Wald DN - Search Results

1

p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG.

Thakur VS, Ruhul Amin AR, Paul RK, Gupta K, Hastak K, Agarwal MK, Jackson MW, Wald DN, Mukhtar H, Agarwal ML. Thakur VS, et al. Among authors: wald dn. Cancer Lett. 2010 Oct 28;296(2):225-32. doi: 10.1016/j.canlet.2010.04.012. Epub 2010 May 4. Cancer Lett. 2010. PMID: 20444544 Free PMC article.

2

Identification of 6-benzylthioinosine as a myeloid leukemia differentiation-inducing compound.

Wald DN, Vermaat HM, Zang S, Lavik A, Kang Z, Peleg G, Gerson SL, Bunting KD, Agarwal ML, Roth BL, Tse W. Wald DN, et al. Cancer Res. 2008 Jun 1;68(11):4369-76. doi: 10.1158/0008-5472.CAN-07-6559. Cancer Res. 2008. PMID: 18519698 Free PMC article.

3

Restoration of p53 functions protects cells from concanavalin A-induced apoptosis.

Amin AR, Thakur VS, Gupta K, Jackson MW, Harada H, Agarwal MK, Shin DM, Wald DN, Agarwal ML. Amin AR, et al. Among authors: wald dn. Mol Cancer Ther. 2010 Feb;9(2):471-9. doi: 10.1158/1535-7163.MCT-09-0732. Epub 2010 Feb 2. Mol Cancer Ther. 2010. PMID: 20124456

4

Securinine induces p73-dependent apoptosis preferentially in p53-deficient colon cancer cells.

Rana S, Gupta K, Gomez J, Matsuyama S, Chakrabarti A, Agarwal ML, Agarwal A, Agarwal MK, Wald DN. Rana S, et al. Among authors: wald dn. FASEB J. 2010 Jun;24(6):2126-34. doi: 10.1096/fj.09-148999. Epub 2010 Feb 4. FASEB J. 2010. PMID: 20133503

5

Securinine, a myeloid differentiation agent with therapeutic potential for AML.

Gupta K, Chakrabarti A, Rana S, Ramdeo R, Roth BL, Agarwal ML, Tse W, Agarwal MK, Wald DN. Gupta K, et al. Among authors: wald dn. PLoS One. 2011;6(6):e21203. doi: 10.1371/journal.pone.0021203. Epub 2011 Jun 24. PLoS One. 2011. PMID: 21731671 Free PMC article.

6

GSK3 is a regulator of RAR-mediated differentiation.

Gupta K, Gulen F, Sun L, Aguilera R, Chakrabarti A, Kiselar J, Agarwal MK, Wald DN. Gupta K, et al. Among authors: wald dn. Leukemia. 2012 Jun;26(6):1277-85. doi: 10.1038/leu.2012.2. Epub 2012 Jan 6. Leukemia. 2012. PMID: 22222598 Free PMC article.

7

N-(phosphonacetyl)-L-aspartate induces TAp73-dependent apoptosis by modulating multiple Bcl-2 proteins: potential for cancer therapy.

Ruhul Amin AR, Thakur VS, Gupta K, Agarwal MK, Wald DN, Shin DM, Agarwal ML. Ruhul Amin AR, et al. Among authors: wald dn. Oncogene. 2013 Feb 14;32(7):920-9. doi: 10.1038/onc.2012.96. Epub 2012 Mar 19. Oncogene. 2013. PMID: 22430213 Free PMC article.

8

ATP depletion triggers acute myeloid leukemia differentiation through an ATR/Chk1 protein-dependent and p53 protein-independent pathway.

Chakrabarti A, Gupta K, Sharma JP, Yang J, Agarwal A, Glick A, Zhang Y, Agarwal M, Agarwal MK, Wald DN. Chakrabarti A, et al. Among authors: wald dn. J Biol Chem. 2012 Jul 6;287(28):23635-43. doi: 10.1074/jbc.M111.312801. Epub 2012 May 23. J Biol Chem. 2012. PMID: 22621920 Free PMC article.

9

The role of TLR8 signaling in acute myeloid leukemia differentiation.

Ignatz-Hoover JJ, Wang H, Moreton SA, Chakrabarti A, Agarwal MK, Sun K, Gupta K, Wald DN. Ignatz-Hoover JJ, et al. Among authors: wald dn. Leukemia. 2015 Apr;29(4):918-926. doi: 10.1038/leu.2014.293. Epub 2014 Oct 6. Leukemia. 2015. PMID: 25283842 Free PMC article.

10

Identification of a Small Molecule That Overcomes HdmX-Mediated Suppression of p53.

Karan G, Wang H, Chakrabarti A, Karan S, Liu Z, Xia Z, Gundluru M, Moreton S, Saunthararajah Y, Jackson MW, Agarwal MK, Wald DN. Karan G, et al. Among authors: wald dn. Mol Cancer Ther. 2016 Apr;15(4):574-582. doi: 10.1158/1535-7163.MCT-15-0467. Epub 2016 Feb 16. Mol Cancer Ther. 2016. PMID: 26883273 Free PMC article.

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