Krauth-Siegel RL - Search Results

1

Bakker BM, Krauth-Siegel RL, Clayton C, Matthews K, Girolami M, Westerhoff HV, Michels PA, Breitling R, Barrett MP. Bakker BM, et al. Parasitology. 2010 Aug;137(9):1333-41. doi: 10.1017/S0031182010000466. Epub 2010 May 6. Parasitology. 2010. PMID: 20444304 Free article. Review.

2

The silicon trypanosome: a test case of iterative model extension in systems biology.

Achcar F, Fadda A, Haanstra JR, Kerkhoven EJ, Kim DH, Leroux AE, Papamarkou T, Rojas F, Bakker BM, Barrett MP, Clayton C, Girolami M, Krauth-Siegel RL, Matthews KR, Breitling R. Achcar F, et al. Adv Microb Physiol. 2014;64:115-43. doi: 10.1016/B978-0-12-800143-1.00003-8. Adv Microb Physiol. 2014. PMID: 24797926 Free PMC article. Review.

3

Silencing of the thioredoxin gene in Trypanosoma brucei brucei.

Schmidt A, Clayton CE, Krauth-Siegel RL. Schmidt A, et al. Mol Biochem Parasitol. 2002 Nov-Dec;125(1-2):207-10. doi: 10.1016/s0166-6851(02)00215-3. Mol Biochem Parasitol. 2002. PMID: 12467989 No abstract available.

4

Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling.

Leroux AE, Haanstra JR, Bakker BM, Krauth-Siegel RL. Leroux AE, et al. J Biol Chem. 2013 Aug 16;288(33):23751-64. doi: 10.1074/jbc.M113.483289. Epub 2013 Jun 28. J Biol Chem. 2013. PMID: 23814051 Free PMC article.

5

Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei.

Shahi SK, Krauth-Siegel RL, Clayton CE. Shahi SK, et al. Mol Microbiol. 2002 Mar;43(5):1129-38. doi: 10.1046/j.1365-2958.2002.02831.x. Mol Microbiol. 2002. PMID: 11918801 Free article.

6

Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains.

Wenzel IN, Wong PE, Maes L, Müller TJ, Krauth-Siegel RL, Barrett MP, Davioud-Charvet E. Wenzel IN, et al. ChemMedChem. 2009 Mar;4(3):339-51. doi: 10.1002/cmdc.200800360. ChemMedChem. 2009. PMID: 19219843

7

Stress-Induced Protein S-Glutathionylation and S-Trypanothionylation in African Trypanosomes-A Quantitative Redox Proteome and Thiol Analysis.

Ulrich K, Finkenzeller C, Merker S, Rojas F, Matthews K, Ruppert T, Krauth-Siegel RL. Ulrich K, et al. Antioxid Redox Signal. 2017 Sep 20;27(9):517-533. doi: 10.1089/ars.2016.6947. Epub 2017 Mar 24. Antioxid Redox Signal. 2017. PMID: 28338335 Free PMC article.

8

Toward the development of dual-targeted glyceraldehyde-3-phosphate dehydrogenase/trypanothione reductase inhibitors against Trypanosoma brucei and Trypanosoma cruzi.

Belluti F, Uliassi E, Veronesi G, Bergamini C, Kaiser M, Brun R, Viola A, Fato R, Michels PA, Krauth-Siegel RL, Cavalli A, Bolognesi ML. Belluti F, et al. ChemMedChem. 2014 Feb;9(2):371-82. doi: 10.1002/cmdc.201300399. Epub 2014 Jan 8. ChemMedChem. 2014. PMID: 24403089

9

Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei.

Schlecker T, Schmidt A, Dirdjaja N, Voncken F, Clayton C, Krauth-Siegel RL. Schlecker T, et al. J Biol Chem. 2005 Apr 15;280(15):14385-94. doi: 10.1074/jbc.M413338200. Epub 2005 Jan 21. J Biol Chem. 2005. PMID: 15664987 Free article.

10

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress.

Krieger S, Schwarz W, Ariyanayagam MR, Fairlamb AH, Krauth-Siegel RL, Clayton C. Krieger S, et al. Mol Microbiol. 2000 Feb;35(3):542-52. doi: 10.1046/j.1365-2958.2000.01721.x. Mol Microbiol. 2000. PMID: 10672177 Free article.

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