Tomar A - Search Results

1

Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.

Lim ST, Chen XL, Tomar A, Miller NL, Yoo J, Schlaepfer DD. Lim ST, et al. Among authors: tomar a. J Biol Chem. 2010 Jul 9;285(28):21526-36. doi: 10.1074/jbc.M110.129999. Epub 2010 May 4. J Biol Chem. 2010. PMID: 20442405 Free PMC article.

2

Tumor necrosis factor-alpha stimulates focal adhesion kinase activity required for mitogen-activated kinase-associated interleukin 6 expression.

Schlaepfer DD, Hou S, Lim ST, Tomar A, Yu H, Lim Y, Hanson DA, Uryu SA, Molina J, Mitra SK. Schlaepfer DD, et al. Among authors: tomar a. J Biol Chem. 2007 Jun 15;282(24):17450-9. doi: 10.1074/jbc.M610672200. Epub 2007 Apr 16. J Biol Chem. 2007. PMID: 17438336 Free article.

3

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility.

Lim Y, Lim ST, Tomar A, Gardel M, Bernard-Trifilo JA, Chen XL, Uryu SA, Canete-Soler R, Zhai J, Lin H, Schlaepfer WW, Nalbant P, Bokoch G, Ilic D, Waterman-Storer C, Schlaepfer DD. Lim Y, et al. Among authors: tomar a. J Cell Biol. 2008 Jan 14;180(1):187-203. doi: 10.1083/jcb.200708194. J Cell Biol. 2008. PMID: 18195107 Free PMC article.

4

A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.

Tomar A, Lim ST, Lim Y, Schlaepfer DD. Tomar A, et al. J Cell Sci. 2009 Jun 1;122(Pt 11):1852-62. doi: 10.1242/jcs.046870. Epub 2009 May 12. J Cell Sci. 2009. PMID: 19435801 Free PMC article.

5

Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility.

Tomar A, Schlaepfer DD. Tomar A, et al. Curr Opin Cell Biol. 2009 Oct;21(5):676-83. doi: 10.1016/j.ceb.2009.05.006. Epub 2009 Jun 12. Curr Opin Cell Biol. 2009. PMID: 19525103 Free PMC article. Review.

6

A PAK-activated linker for EGFR and FAK.

Tomar A, Schlaepfer DD. Tomar A, et al. Dev Cell. 2010 Feb 16;18(2):170-2. doi: 10.1016/j.devcel.2010.01.013. Dev Cell. 2010. PMID: 20159588 Free PMC article.

7

p190RhoGEF (Rgnef) promotes colon carcinoma tumor progression via interaction with focal adhesion kinase.

Yu HG, Nam JO, Miller NL, Tanjoni I, Walsh C, Shi L, Kim L, Chen XL, Tomar A, Lim ST, Schlaepfer DD. Yu HG, et al. Among authors: tomar a. Cancer Res. 2011 Jan 15;71(2):360-70. doi: 10.1158/0008-5472.CAN-10-2894. Epub 2011 Jan 11. Cancer Res. 2011. PMID: 21224360 Free PMC article.

8

Cortactin as a target for FAK in the regulation of focal adhesion dynamics.

Tomar A, Lawson C, Ghassemian M, Schlaepfer DD. Tomar A, et al. PLoS One. 2012;7(8):e44041. doi: 10.1371/journal.pone.0044041. Epub 2012 Aug 29. PLoS One. 2012. PMID: 22952866 Free PMC article.

9

PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.

Tanjoni I, Walsh C, Uryu S, Tomar A, Nam JO, Mielgo A, Lim ST, Liang C, Koenig M, Sun C, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Tanjoni I, et al. Among authors: tomar a. Cancer Biol Ther. 2010 May 15;9(10):764-77. doi: 10.4161/cbt.9.10.11434. Cancer Biol Ther. 2010. PMID: 20234191 Free PMC article.

10

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models.

Walsh C, Tanjoni I, Uryu S, Tomar A, Nam JO, Luo H, Phillips A, Patel N, Kwok C, McMahon G, Stupack DG, Schlaepfer DD. Walsh C, et al. Among authors: tomar a. Cancer Biol Ther. 2010 May 15;9(10):778-90. doi: 10.4161/cbt.9.10.11433. Cancer Biol Ther. 2010. PMID: 20234193 Free PMC article.

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