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A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.
Yu T, Li Z, Jia Z, Clapcote SJ, Liu C, Li S, Asrar S, Pao A, Chen R, Fan N, Carattini-Rivera S, Bechard AR, Spring S, Henkelman RM, Stoica G, Matsui S, Nowak NJ, Roder JC, Chen C, Bradley A, Yu YE. Yu T, et al. Among authors: clapcote sj. Hum Mol Genet. 2010 Jul 15;19(14):2780-91. doi: 10.1093/hmg/ddq179. Epub 2010 May 4. Hum Mol Genet. 2010. PMID: 20442137 Free PMC article.
Deficiencies in the region syntenic to human 21q22.3 cause cognitive deficits in mice.
Yu T, Clapcote SJ, Li Z, Liu C, Pao A, Bechard AR, Carattini-Rivera S, Matsui S, Roder JC, Baldini A, Mobley WC, Bradley A, Yu YE. Yu T, et al. Among authors: clapcote sj. Mamm Genome. 2010 Jun;21(5-6):258-67. doi: 10.1007/s00335-010-9262-x. Epub 2010 May 29. Mamm Genome. 2010. PMID: 20512340 Free PMC article.
Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.
Yu T, Liu C, Belichenko P, Clapcote SJ, Li S, Pao A, Kleschevnikov A, Bechard AR, Asrar S, Chen R, Fan N, Zhou Z, Jia Z, Chen C, Roder JC, Liu B, Baldini A, Mobley WC, Yu YE. Yu T, et al. Among authors: clapcote sj. Brain Res. 2010 Dec 17;1366:162-71. doi: 10.1016/j.brainres.2010.09.107. Epub 2010 Oct 26. Brain Res. 2010. PMID: 20932954 Free PMC article.
Genetic analysis of Down syndrome facilitated by mouse chromosome engineering.
Zhang L, Fu D, Belichenko PV, Liu C, Kleschevnikov AM, Pao A, Liang P, Clapcote SJ, Mobley WC, Yu YE. Zhang L, et al. Among authors: clapcote sj. Bioeng Bugs. 2012 Jan 1;3(1):8-12. doi: 10.4161/bbug.3.1.17696. Epub 2012 Jan 1. Bioeng Bugs. 2012. PMID: 22126738 Free PMC article.
63 results