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Page 1
Reprogramming of miRNA networks in cancer and leukemia.
Volinia S, Galasso M, Costinean S, Tagliavini L, Gamberoni G, Drusco A, Marchesini J, Mascellani N, Sana ME, Abu Jarour R, Desponts C, Teitell M, Baffa R, Aqeilan R, Iorio MV, Taccioli C, Garzon R, Di Leva G, Fabbri M, Catozzi M, Previati M, Ambs S, Palumbo T, Garofalo M, Veronese A, Bottoni A, Gasparini P, Harris CC, Visone R, Pekarsky Y, de la Chapelle A, Bloomston M, Dillhoff M, Rassenti LZ, Kipps TJ, Huebner K, Pichiorri F, Lenze D, Cairo S, Buendia MA, Pineau P, Dejean A, Zanesi N, Rossi S, Calin GA, Liu CG, Palatini J, Negrini M, Vecchione A, Rosenberg A, Croce CM. Volinia S, et al. Among authors: lenze d. Genome Res. 2010 May;20(5):589-99. doi: 10.1101/gr.098046.109. Genome Res. 2010. PMID: 20439436 Free PMC article.
The different epidemiologic subtypes of Burkitt lymphoma share a homogenous micro RNA profile distinct from diffuse large B-cell lymphoma.
Lenze D, Leoncini L, Hummel M, Volinia S, Liu CG, Amato T, De Falco G, Githanga J, Horn H, Nyagol J, Ott G, Palatini J, Pfreundschuh M, Rogena E, Rosenwald A, Siebert R, Croce CM, Stein H. Lenze D, et al. Leukemia. 2011 Dec;25(12):1869-1876. doi: 10.1038/leu.2011.156. Epub 2011 Jun 24. Leukemia. 2011. PMID: 21701491 Free PMC article.
A modular transcriptome map of mature B cell lymphomas.
Loeffler-Wirth H, Kreuz M, Hopp L, Arakelyan A, Haake A, Cogliatti SB, Feller AC, Hansmann ML, Lenze D, Möller P, Müller-Hermelink HK, Fortenbacher E, Willscher E, Ott G, Rosenwald A, Pott C, Schwaenen C, Trautmann H, Wessendorf S, Stein H, Szczepanowski M, Trümper L, Hummel M, Klapper W, Siebert R, Loeffler M, Binder H; German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma. Loeffler-Wirth H, et al. Among authors: lenze d. Genome Med. 2019 Apr 30;11(1):27. doi: 10.1186/s13073-019-0637-7. Genome Med. 2019. PMID: 31039827 Free PMC article.
Senescence-associated reprogramming promotes cancer stemness.
Milanovic M, Fan DNY, Belenki D, Däbritz JHM, Zhao Z, Yu Y, Dörr JR, Dimitrova L, Lenze D, Monteiro Barbosa IA, Mendoza-Parra MA, Kanashova T, Metzner M, Pardon K, Reimann M, Trumpp A, Dörken B, Zuber J, Gronemeyer H, Hummel M, Dittmar G, Lee S, Schmitt CA. Milanovic M, et al. Among authors: lenze d. Nature. 2018 Jan 4;553(7686):96-100. doi: 10.1038/nature25167. Epub 2017 Dec 20. Nature. 2018. PMID: 29258294
Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors.
De Falco G, Leucci E, Lenze D, Piccaluga PP, Claudio PP, Onnis A, Cerino G, Nyagol J, Mwanda W, Bellan C, Hummel M, Pileri S, Tosi P, Stein H, Giordano A, Leoncini L. De Falco G, et al. Among authors: lenze d. Blood. 2007 Aug 15;110(4):1301-7. doi: 10.1182/blood-2006-12-064865. Epub 2007 May 7. Blood. 2007. PMID: 17485552 Free article.
Different biological risk factors in young poor-prognosis and elderly patients with diffuse large B-cell lymphoma.
Horn H, Ziepert M, Wartenberg M, Staiger AM, Barth TF, Bernd HW, Feller AC, Klapper W, Stuhlmann-Laeisz C, Hummel M, Stein H, Lenze D, Hartmann S, Hansmann ML, Möller P, Cogliatti S, Pfreundschuh M, Trümper L, Loeffler M, Glass B, Schmitz N, Ott G, Rosenwald A; DSHNHL16. Horn H, et al. Among authors: lenze d. Leukemia. 2015 Jul;29(7):1564-70. doi: 10.1038/leu.2015.43. Epub 2015 Feb 17. Leukemia. 2015. PMID: 25687653
Similar clinical features in follicular lymphomas with and without breaks in the BCL2 locus.
Leich E, Hoster E, Wartenberg M, Unterhalt M, Siebert R, Koch K, Klapper W, Engelhard M, Puppe B, Horn H, Staiger AM, Stuhlmann-Laeisz C, Bernd HW, Feller AC, Hummel M, Lenze D, Stein H, Hartmann S, Hansmann ML, Möller P, Hiddemann W, Dreyling M, Ott G, Rosenwald A; German Low Grade Lymphoma Study Group (GLSG). Leich E, et al. Among authors: lenze d. Leukemia. 2016 Apr;30(4):854-60. doi: 10.1038/leu.2015.330. Epub 2015 Dec 1. Leukemia. 2016. PMID: 26621338
Differences between BCL2-break positive and negative follicular lymphoma unraveled by whole-exome sequencing.
Zamò A, Pischimarov J, Schlesner M, Rosenstiel P, Bomben R, Horn H, Grieb T, Nedeva T, López C, Haake A, Richter J, Trümper L, Lawerenz C, Klapper W, Möller P, Hummel M, Lenze D, Szczepanowski M, Flossbach L, Schreder M, Gattei V, Ott G, Siebert R, Rosenwald A, Leich E. Zamò A, et al. Among authors: lenze d. Leukemia. 2018 Mar;32(3):685-693. doi: 10.1038/leu.2017.270. Epub 2017 Aug 21. Leukemia. 2018. PMID: 28824170
Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma.
Dierlamm J, Murga Penas EM, Bentink S, Wessendorf S, Berger H, Hummel M, Klapper W, Lenze D, Rosenwald A, Haralambieva E, Ott G, Cogliatti SB, Möller P, Schwaenen C, Stein H, Löffler M, Spang R, Trümper L, Siebert R; Deutsche Krebshilfe Network Project "Molecular Mechanisms in Malignant Lymphomas". Dierlamm J, et al. Among authors: lenze d. Haematologica. 2008 May;93(5):688-96. doi: 10.3324/haematol.12057. Epub 2008 Mar 26. Haematologica. 2008. PMID: 18367485 Free article.
Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas.
Hübschmann D, Kleinheinz K, Wagener R, Bernhart SH, López C, Toprak UH, Sungalee S, Ishaque N, Kretzmer H, Kreuz M, Waszak SM, Paramasivam N, Ammerpohl O, Aukema SM, Beekman R, Bergmann AK, Bieg M, Binder H, Borkhardt A, Borst C, Brors B, Bruns P, Carrillo de Santa Pau E, Claviez A, Doose G, Haake A, Karsch D, Haas S, Hansmann ML, Hoell JI, Hovestadt V, Huang B, Hummel M, Jäger-Schmidt C, Kerssemakers JNA, Korbel JO, Kube D, Lawerenz C, Lenze D, Martens JHA, Ott G, Radlwimmer B, Reisinger E, Richter J, Rico D, Rosenstiel P, Rosenwald A, Schillhabel M, Stilgenbauer S, Stadler PF, Martín-Subero JI, Szczepanowski M, Warsow G, Weniger MA, Zapatka M, Valencia A, Stunnenberg HG, Lichter P, Möller P, Loeffler M, Eils R, Klapper W, Hoffmann S, Trümper L; ICGC MMML-Seq consortium; ICGC DE-Mining consortium; BLUEPRINT consortium; Küppers R, Schlesner M, Siebert R. Hübschmann D, et al. Among authors: lenze d. Leukemia. 2021 Jul;35(7):2002-2016. doi: 10.1038/s41375-021-01251-z. Epub 2021 May 5. Leukemia. 2021. PMID: 33953289 Free PMC article.
157 results