Stambrook PJ - Search Results

1

Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.

Meyer SE, Peace BE, Bahassi el M, Kavanaugh GM, Wagh PK, Robbins SB, Yin M, Wells SI, Zinser GM, Stambrook PJ, Waltz SE. Meyer SE, et al. Among authors: stambrook pj. Cancer Lett. 2010 Oct 28;296(2):186-93. doi: 10.1016/j.canlet.2010.04.011. Cancer Lett. 2010. PMID: 20434834 Free PMC article.

2

The breast cancer susceptibility allele CHEK2*1100delC promotes genomic instability in a knock-in mouse model.

Bahassi el M, Penner CG, Robbins SB, Tichy E, Feliciano E, Yin M, Liang L, Deng L, Tischfield JA, Stambrook PJ. Bahassi el M, et al. Among authors: stambrook pj. Mutat Res. 2007 Mar 1;616(1-2):201-9. doi: 10.1016/j.mrfmmm.2006.11.025. Epub 2006 Dec 15. Mutat Res. 2007. PMID: 17174984

3

Mice with the CHEK2*1100delC SNP are predisposed to cancer with a strong gender bias.

Bahassi el M, Robbins SB, Yin M, Boivin GP, Kuiper R, van Steeg H, Stambrook PJ. Bahassi el M, et al. Among authors: stambrook pj. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17111-6. doi: 10.1073/pnas.0909237106. Epub 2009 Sep 21. Proc Natl Acad Sci U S A. 2009. PMID: 19805189 Free PMC article.

4

Absence of polo-like kinase 3 in mice stabilizes Cdc25A after DNA damage but is not sufficient to produce tumors.

Myer DL, Robbins SB, Yin M, Boivin GP, Liu Y, Greis KD, Bahassi el M, Stambrook PJ. Myer DL, et al. Among authors: stambrook pj. Mutat Res. 2011 Sep 1;714(1-2):1-10. doi: 10.1016/j.mrfmmm.2011.02.006. Epub 2011 Mar 3. Mutat Res. 2011. PMID: 21376736 Free PMC article.

5

The human DEK oncogene regulates DNA damage response signaling and repair.

Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, Wells SI. Kavanaugh GM, et al. Among authors: stambrook pj. Nucleic Acids Res. 2011 Sep 1;39(17):7465-76. doi: 10.1093/nar/gkr454. Epub 2011 Jun 7. Nucleic Acids Res. 2011. PMID: 21653549 Free PMC article.

6

A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer.

Bahassi el M, Li YQ, Wise-Draper TM, Deng L, Wang J, Darnell CN, Wilson KM, Wells SI, Stambrook PJ, Rixe O. Bahassi el M, et al. Among authors: stambrook pj. Eur J Cancer. 2013 Jul;49(10):2345-55. doi: 10.1016/j.ejca.2013.03.005. Epub 2013 Apr 8. Eur J Cancer. 2013. PMID: 23578570 Free PMC article.

7

Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways.

Bahassi el M, Conn CW, Myer DL, Hennigan RF, McGowan CH, Sanchez Y, Stambrook PJ. Bahassi el M, et al. Among authors: stambrook pj. Oncogene. 2002 Sep 26;21(43):6633-40. doi: 10.1038/sj.onc.1205850. Oncogene. 2002. PMID: 12242661

8

Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation.

Bahassi el M, Hennigan RF, Myer DL, Stambrook PJ. Bahassi el M, et al. Among authors: stambrook pj. Oncogene. 2004 Apr 8;23(15):2658-63. doi: 10.1038/sj.onc.1207425. Oncogene. 2004. PMID: 14968113

9

The Plk3-Cdc25 circuit.

Myer DL, Bahassi el M, Stambrook PJ. Myer DL, et al. Among authors: stambrook pj. Oncogene. 2005 Jan 10;24(2):299-305. doi: 10.1038/sj.onc.1208278. Oncogene. 2005. PMID: 15640846 Review.

10

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.

Bahassi el M, Myer DL, McKenney RJ, Hennigan RF, Stambrook PJ. Bahassi el M, et al. Among authors: stambrook pj. Mutat Res. 2006 Apr 11;596(1-2):166-76. doi: 10.1016/j.mrfmmm.2005.12.002. Epub 2006 Feb 14. Mutat Res. 2006. PMID: 16481012

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