Bradshaw TD - Search Results

1

Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions.

McCarroll AJ, Matthews CS, Wells G, Bradshaw TD, Stevens MF. McCarroll AJ, et al. Among authors: bradshaw td. Org Biomol Chem. 2010 May 7;8(9):2078-84. doi: 10.1039/b920039h. Epub 2010 Mar 3. Org Biomol Chem. 2010. PMID: 20401384

2

Antitumor benzothiazoles. 3. Synthesis of 2-(4-aminophenyl)benzothiazoles and evaluation of their activities against breast cancer cell lines in vitro and in vivo.

Shi DF, Bradshaw TD, Wrigley S, McCall CJ, Lelieveld P, Fichtner I, Stevens MF. Shi DF, et al. Among authors: bradshaw td. J Med Chem. 1996 Aug 16;39(17):3375-84. doi: 10.1021/jm9600959. J Med Chem. 1996. PMID: 8765521

3

2-(4-Aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity.

Bradshaw TD, Wrigley S, Shi DF, Schultz RJ, Paull KD, Stevens MF. Bradshaw TD, et al. Br J Cancer. 1998 Mar;77(5):745-52. doi: 10.1038/bjc.1998.122. Br J Cancer. 1998. PMID: 9514053 Free PMC article.

4

Influence of 2-(4-aminophenyl)benzothiazoles on growth of human ovarian carcinoma cells in vitro and in vivo.

Bradshaw TD, Shi DF, Schultz RJ, Paull KD, Kelland L, Wilson A, Garner C, Fiebig HH, Wrigley S, Stevens MF. Bradshaw TD, et al. Br J Cancer. 1998 Aug;78(4):421-9. doi: 10.1038/bjc.1998.510. Br J Cancer. 1998. PMID: 9716022 Free PMC article.

5

Antitumor benzothiazoles. 7. Synthesis of 2-(4-acylaminophenyl)benzothiazoles and investigations into the role of acetylation in the antitumor activities of the parent amines.

Chua MS, Shi DF, Wrigley S, Bradshaw TD, Hutchinson I, Shaw PN, Barrett DA, Stanley LA, Stevens MF. Chua MS, et al. Among authors: bradshaw td. J Med Chem. 1999 Feb 11;42(3):381-92. doi: 10.1021/jm981076x. J Med Chem. 1999. PMID: 9986708

6

Antitumor benzothiazoles. 8. Synthesis, metabolic formation, and biological properties of the C- and N-oxidation products of antitumor 2-(4-aminophenyl)benzothiazoles.

Kashiyama E, Hutchinson I, Chua MS, Stinson SF, Phillips LR, Kaur G, Sausville EA, Bradshaw TD, Westwell AD, Stevens MF. Kashiyama E, et al. Among authors: bradshaw td. J Med Chem. 1999 Oct 7;42(20):4172-84. doi: 10.1021/jm990104o. J Med Chem. 1999. PMID: 10514287

7

Antitumour benzothiazoles. Part 10: the synthesis and antitumour activity of benzothiazole substituted quinol derivatives.

Wells G, Bradshaw TD, Diana P, Seaton A, Shi DF, Westwell AD, Stevens MF. Wells G, et al. Among authors: bradshaw td. Bioorg Med Chem Lett. 2000 Mar 6;10(5):513-5. doi: 10.1016/s0960-894x(00)00027-5. Bioorg Med Chem Lett. 2000. PMID: 10743960

8

Mechanisms of acquired resistance to 2-(4-aminophenyl)benzothiazole (CJM 126, NSC 34445).

Bradshaw TD, Chua MS, Orr S, Matthews CS, Stevens MF. Bradshaw TD, et al. Br J Cancer. 2000 Jul;83(2):270-7. doi: 10.1054/bjoc.2000.1231. Br J Cancer. 2000. PMID: 10901382 Free PMC article.

9

Role of Cyp1A1 in modulation of antitumor properties of the novel agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203, NSC 674495) in human breast cancer cells.

Chua MS, Kashiyama E, Bradshaw TD, Stinson SF, Brantley E, Sausville EA, Stevens MF. Chua MS, et al. Among authors: bradshaw td. Cancer Res. 2000 Sep 15;60(18):5196-203. Cancer Res. 2000. PMID: 11016648

10

The discovery of the potent and selective antitumour agent 2-(4-amino-3-methylphenyl)benzothiazole (DF 203) and related compounds.

Bradshaw TD, Stevens MF, Westwell AD. Bradshaw TD, et al. Curr Med Chem. 2001 Feb;8(2):203-10. doi: 10.2174/0929867013373714. Curr Med Chem. 2001. PMID: 11172675 Review.

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