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New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
López-Ramos M, Prudent R, Moucadel V, Sautel CF, Barette C, Lafanechère L, Mouawad L, Grierson D, Schmidt F, Florent JC, Filippakopoulos P, Bullock AN, Knapp S, Reiser JB, Cochet C. López-Ramos M, et al. Among authors: florent jc. FASEB J. 2010 Sep;24(9):3171-85. doi: 10.1096/fj.09-143743. Epub 2010 Apr 16. FASEB J. 2010. PMID: 20400536
Salicylaldehyde derivatives as new protein kinase CK2 inhibitors.
Prudent R, López-Ramos M, Moucadel V, Barette C, Grierson D, Mouawad L, Florent JC, Lafanechère L, Schmidt F, Cochet C. Prudent R, et al. Among authors: florent jc. Biochim Biophys Acta. 2008 Dec;1780(12):1412-20. doi: 10.1016/j.bbagen.2008.06.010. Epub 2008 Jul 7. Biochim Biophys Acta. 2008. PMID: 18674590
Expanding the chemical diversity of CK2 inhibitors.
Prudent R, Moucadel V, López-Ramos M, Aci S, Laudet B, Mouawad L, Barette C, Einhorn J, Einhorn C, Denis JN, Bisson G, Schmidt F, Roy S, Lafanechere L, Florent JC, Cochet C. Prudent R, et al. Among authors: florent jc. Mol Cell Biochem. 2008 Sep;316(1-2):71-85. doi: 10.1007/s11010-008-9828-z. Epub 2008 Jun 18. Mol Cell Biochem. 2008. PMID: 18563535
Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth.
Prudent R, Vassal-Stermann E, Nguyen CH, Pillet C, Martinez A, Prunier C, Barette C, Soleilhac E, Filhol O, Beghin A, Valdameri G, Honoré S, Aci-Sèche S, Grierson D, Antonipillai J, Li R, Di Pietro A, Dumontet C, Braguer D, Florent JC, Knapp S, Bernard O, Lafanechère L. Prudent R, et al. Among authors: florent jc. Cancer Res. 2012 Sep 1;72(17):4429-39. doi: 10.1158/0008-5472.CAN-11-3342. Epub 2012 Jul 3. Cancer Res. 2012. PMID: 22761334 Free article.
Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.
Prudent R, Vassal-Stermann É, Nguyen CH, Mollaret M, Viallet J, Desroches-Castan A, Martinez A, Barette C, Pillet C, Valdameri G, Soleilhac E, Di Pietro A, Feige JJ, Billaud M, Florent JC, Lafanechère L. Prudent R, et al. Among authors: florent jc. Br J Pharmacol. 2013 Feb;168(3):673-85. doi: 10.1111/j.1476-5381.2012.02230.x. Br J Pharmacol. 2013. PMID: 23004938 Free PMC article.
62 results