Schulman IG - Search Results

1

Non-redundant roles for LXRalpha and LXRbeta in atherosclerosis susceptibility in low density lipoprotein receptor knockout mice.

Bischoff ED, Daige CL, Petrowski M, Dedman H, Pattison J, Juliano J, Li AC, Schulman IG. Bischoff ED, et al. Among authors: schulman ig. J Lipid Res. 2010 May;51(5):900-6. doi: 10.1194/jlr.M900096. J Lipid Res. 2010. PMID: 20388921 Free PMC article.

2

Identification of macrophage liver X receptors as inhibitors of atherosclerosis.

Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Tangirala RK, et al. Among authors: schulman ig. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11896-901. doi: 10.1073/pnas.182199799. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193651 Free PMC article.

3

Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR).

Flatt B, Martin R, Wang TL, Mahaney P, Murphy B, Gu XH, Foster P, Li J, Pircher P, Petrowski M, Schulman I, Westin S, Wrobel J, Yan G, Bischoff E, Daige C, Mohan R. Flatt B, et al. J Med Chem. 2009 Feb 26;52(4):904-7. doi: 10.1021/jm8014124. J Med Chem. 2009. PMID: 19159286

4

Regulation of cholesterol homeostasis and lipid metabolism in skeletal muscle by liver X receptors.

Muscat GE, Wagner BL, Hou J, Tangirala RK, Bischoff ED, Rohde P, Petrowski M, Li J, Shao G, Macondray G, Schulman IG. Muscat GE, et al. Among authors: schulman ig. J Biol Chem. 2002 Oct 25;277(43):40722-8. doi: 10.1074/jbc.M206681200. Epub 2002 Aug 21. J Biol Chem. 2002. PMID: 12193599 Free article.

5

Farnesoid X receptor regulates bile acid-amino acid conjugation.

Pircher PC, Kitto JL, Petrowski ML, Tangirala RK, Bischoff ED, Schulman IG, Westin SK. Pircher PC, et al. Among authors: schulman ig. J Biol Chem. 2003 Jul 25;278(30):27703-11. doi: 10.1074/jbc.M302128200. Epub 2003 May 16. J Biol Chem. 2003. PMID: 12754200 Free article.

6

Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression.

Wagner BL, Valledor AF, Shao G, Daige CL, Bischoff ED, Petrowski M, Jepsen K, Baek SH, Heyman RA, Rosenfeld MG, Schulman IG, Glass CK. Wagner BL, et al. Among authors: schulman ig. Mol Cell Biol. 2003 Aug;23(16):5780-9. doi: 10.1128/MCB.23.16.5780-5789.2003. Mol Cell Biol. 2003. PMID: 12897148 Free PMC article.

7

Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists.

Levin N, Bischoff ED, Daige CL, Thomas D, Vu CT, Heyman RA, Tangirala RK, Schulman IG. Levin N, et al. Among authors: schulman ig. Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):135-42. doi: 10.1161/01.ATV.0000150044.84012.68. Epub 2004 Nov 11. Arterioscler Thromb Vasc Biol. 2005. PMID: 15539622

8

Regulation of metabolism by nuclear hormone receptors.

Huang HJ, Schulman IG. Huang HJ, et al. Among authors: schulman ig. Prog Mol Biol Transl Sci. 2009;87:1-51. doi: 10.1016/S1877-1173(09)87001-4. Epub 2009 Oct 7. Prog Mol Biol Transl Sci. 2009. PMID: 20374700 Review.

9

The flip side: Identifying small molecule regulators of nuclear receptors.

Schulman IG, Heyman RA. Schulman IG, et al. Chem Biol. 2004 May;11(5):639-46. doi: 10.1016/j.chembiol.2003.12.021. Chem Biol. 2004. PMID: 15157874 Review.

10

Liver X receptor (LXR) partial agonists: biaryl pyrazoles and imidazoles displaying a preference for LXRβ.

Kick E, Martin R, Xie Y, Flatt B, Schweiger E, Wang TL, Busch B, Nyman M, Gu XH, Yan G, Wagner B, Nanao M, Nguyen L, Stout T, Plonowski A, Schulman I, Ostrowski J, Kirchgessner T, Wexler R, Mohan R. Kick E, et al. Bioorg Med Chem Lett. 2015 Jan 15;25(2):372-7. doi: 10.1016/j.bmcl.2014.11.029. Epub 2014 Nov 15. Bioorg Med Chem Lett. 2015. PMID: 25435151

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