Gaspar A - Search Results

1

Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.

Alcaro S, Gaspar A, Ortuso F, Milhazes N, Orallo F, Uriarte E, Yáñez M, Borges F. Alcaro S, et al. Among authors: gaspar a. Bioorg Med Chem Lett. 2010 May 1;20(9):2709-12. doi: 10.1016/j.bmcl.2010.03.081. Epub 2010 Mar 27. Bioorg Med Chem Lett. 2010. PMID: 20382016

2

New insights into the antioxidant activity of hydroxycinnamic acids: Synthesis and physicochemical characterization of novel halogenated derivatives.

Gaspar A, Garrido EM, Esteves M, Quezada E, Milhazes N, Garrido J, Borges F. Gaspar A, et al. Eur J Med Chem. 2009 May;44(5):2092-9. doi: 10.1016/j.ejmech.2008.10.027. Epub 2008 Nov 5. Eur J Med Chem. 2009. PMID: 19058883

3

Chromone 3-phenylcarboxamides as potent and selective MAO-B inhibitors.

Gaspar A, Reis J, Fonseca A, Milhazes N, Viña D, Uriarte E, Borges F. Gaspar A, et al. Bioorg Med Chem Lett. 2011 Jan 15;21(2):707-9. doi: 10.1016/j.bmcl.2010.11.128. Epub 2010 Dec 5. Bioorg Med Chem Lett. 2011. PMID: 21194943

4

Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates.

Menezes JC, Kamat SP, Cavaleiro JA, Gaspar A, Garrido J, Borges F. Menezes JC, et al. Among authors: gaspar a. Eur J Med Chem. 2011 Feb;46(2):773-7. doi: 10.1016/j.ejmech.2010.12.016. Epub 2010 Dec 21. Eur J Med Chem. 2011. PMID: 21216503

5

Towards the discovery of a novel class of monoamine oxidase inhibitors: structure-property-activity and docking studies on chromone amides.

Gaspar A, Teixeira F, Uriarte E, Milhazes N, Melo A, Cordeiro MN, Ortuso F, Alcaro S, Borges F. Gaspar A, et al. ChemMedChem. 2011 Apr 4;6(4):628-32. doi: 10.1002/cmdc.201000452. Epub 2011 Jan 25. ChemMedChem. 2011. PMID: 21442758 No abstract available.

6

Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors.

Gaspar A, Silva T, Yáñez M, Vina D, Orallo F, Ortuso F, Uriarte E, Alcaro S, Borges F. Gaspar A, et al. J Med Chem. 2011 Jul 28;54(14):5165-73. doi: 10.1021/jm2004267. Epub 2011 Jul 1. J Med Chem. 2011. PMID: 21696156

7

Discovery of novel A3 adenosine receptor ligands based on chromone scaffold.

Gaspar A, Reis J, Kachler S, Paoletta S, Uriarte E, Klotz KN, Moro S, Borges F. Gaspar A, et al. Biochem Pharmacol. 2012 Jul 1;84(1):21-9. doi: 10.1016/j.bcp.2012.03.007. Epub 2012 Mar 17. Biochem Pharmacol. 2012. PMID: 22433284

8

In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-γ-pyrone skeleton.

Gaspar A, Reis J, Matos MJ, Uriarte E, Borges F. Gaspar A, et al. Eur J Med Chem. 2012 Aug;54:914-8. doi: 10.1016/j.ejmech.2012.05.033. Epub 2012 Jun 1. Eur J Med Chem. 2012. PMID: 22703703

9

Combining QSAR classification models for predictive modeling of human monoamine oxidase inhibitors.

Helguera AM, Pérez-Garrido A, Gaspar A, Reis J, Cagide F, Vina D, Cordeiro MN, Borges F. Helguera AM, et al. Among authors: gaspar a. Eur J Med Chem. 2013 Jan;59:75-90. doi: 10.1016/j.ejmech.2012.10.035. Epub 2012 Nov 1. Eur J Med Chem. 2013. PMID: 23207409

10

Targeting adenosine receptors with coumarins: synthesis and binding activities of amide and carbamate derivatives.

Matos MJ, Gaspar A, Kachler S, Klotz KN, Borges F, Santana L, Uriarte E. Matos MJ, et al. Among authors: gaspar a. J Pharm Pharmacol. 2013 Jan;65(1):30-4. doi: 10.1111/j.2042-7158.2012.01571.x. J Pharm Pharmacol. 2013. PMID: 23215685

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