Chen W - Search Results

1

Novel selective antagonist of the cannabinoid CB1 receptor, MJ15, with prominent anti-obesity effect in rodent models.

Chen W, Tang H, Liu H, Long L, Gong Z, Zheng J, Chi M, Xie Y, Zheng Z, Li S, Wang L. Chen W, et al. Eur J Pharmacol. 2010 Jul 10;637(1-3):178-85. doi: 10.1016/j.ejphar.2010.03.040. Epub 2010 Apr 7. Eur J Pharmacol. 2010. PMID: 20380831

2

Peroxisome proliferator-activated receptor delta-agonist, GW501516, ameliorates insulin resistance, improves dyslipidaemia in monosodium L-glutamate metabolic syndrome mice.

Chen W, Wang LL, Liu HY, Long L, Li S. Chen W, et al. Basic Clin Pharmacol Toxicol. 2008 Sep;103(3):240-6. doi: 10.1111/j.1742-7843.2008.00268.x. Epub 2008 Jul 18. Basic Clin Pharmacol Toxicol. 2008. PMID: 18684227 Free article.

3

P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice.

Chen W, Zhou XB, Liu HY, Xu C, Wang LL, Li S. Chen W, et al. Br J Pharmacol. 2009 Jul;157(5):724-35. doi: 10.1111/j.1476-5381.2009.00231.x. Epub 2009 May 5. Br J Pharmacol. 2009. PMID: 19422369 Free PMC article.

4

(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl) propanoic acid compounds: synthesis and biological evaluation of dual PPARalpha/gamma agonists.

Zhou X, Chen W, Xu C, Fan S, Xie Y, Zhong W, Wang L, Li S. Zhou X, et al. Among authors: chen w. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2605-8. doi: 10.1016/j.bmcl.2010.02.071. Epub 2010 Mar 1. Bioorg Med Chem Lett. 2010. PMID: 20299214

5

Design, synthesis and biological evaluation of novel acrylamide analogues as inhibitors of BCR-ABL kinase.

Li S, Yao Z, Zhao Y, Chen W, Wang H, Kuang X, Zhan W, Yao S, Yu S, Hu W. Li S, et al. Among authors: chen w. Bioorg Med Chem Lett. 2012 Aug 15;22(16):5279-82. doi: 10.1016/j.bmcl.2012.06.044. Epub 2012 Jun 21. Bioorg Med Chem Lett. 2012. PMID: 22789429

6

Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells.

Peng C, Fu X, Wang K, Chen L, Luo B, Huang N, Luo Y, Chen W. Peng C, et al. Among authors: chen l, chen w. Eur J Pharmacol. 2022 Jan 5;914:174461. doi: 10.1016/j.ejphar.2021.174461. Epub 2021 Aug 29. Eur J Pharmacol. 2022. PMID: 34469757

7

Selective inhibition of β-N-acetylhexosaminidases by thioglycosyl-naphthalimide hybrid molecules.

Chen W, Shen S, Dong L, Zhang J, Yang Q. Chen W, et al. Bioorg Med Chem. 2018 Jan 15;26(2):394-400. doi: 10.1016/j.bmc.2017.11.042. Epub 2017 Nov 28. Bioorg Med Chem. 2018. PMID: 29242020

8

Topoisomerase II inhibitors from the roots of Stellera chamaejasme L.

Liu LP, Han K, Chen W, Zhang YY, Tong LJ, Peng T, Xie H, Ding J, Wang HB. Liu LP, et al. Among authors: chen w. Bioorg Med Chem. 2014 Aug 1;22(15):4198-203. doi: 10.1016/j.bmc.2014.05.042. Epub 2014 May 29. Bioorg Med Chem. 2014. PMID: 24931277

9

Synthesis and biological evaluation of novel alkyl diamine linked bivalent β-carbolines as angiogenesis inhibitors.

Chen W, Zhang G, Guo L, Fan W, Ma Q, Zhang X, Du R, Cao R. Chen W, et al. Eur J Med Chem. 2016 Nov 29;124:249-261. doi: 10.1016/j.ejmech.2016.08.050. Epub 2016 Aug 23. Eur J Med Chem. 2016. PMID: 27592394

10

Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors.

Dong G, Chen W, Wang X, Yang X, Xu T, Wang P, Zhang W, Rao Y, Miao C, Sheng C. Dong G, et al. Among authors: chen w. J Med Chem. 2017 Oct 12;60(19):7965-7983. doi: 10.1021/acs.jmedchem.7b00467. Epub 2017 Sep 21. J Med Chem. 2017. PMID: 28885834

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