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Page 1
Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
Fiskus W, Wang Y, Sreekumar A, Buckley KM, Shi H, Jillella A, Ustun C, Rao R, Fernandez P, Chen J, Balusu R, Koul S, Atadja P, Marquez VE, Bhalla KN. Fiskus W, et al. Among authors: buckley km. Blood. 2009 Sep 24;114(13):2733-43. doi: 10.1182/blood-2009-03-213496. Epub 2009 Jul 28. Blood. 2009. PMID: 19638619 Free PMC article.
Cotreatment with panobinostat and JAK2 inhibitor TG101209 attenuates JAK2V617F levels and signaling and exerts synergistic cytotoxic effects against human myeloproliferative neoplastic cells.
Wang Y, Fiskus W, Chong DG, Buckley KM, Natarajan K, Rao R, Joshi A, Balusu R, Koul S, Chen J, Savoie A, Ustun C, Jillella AP, Atadja P, Levine RL, Bhalla KN. Wang Y, et al. Among authors: buckley km. Blood. 2009 Dec 3;114(24):5024-33. doi: 10.1182/blood-2009-05-222133. Epub 2009 Oct 14. Blood. 2009. PMID: 19828702 Free PMC article.
Role of CAAT/enhancer binding protein homologous protein in panobinostat-mediated potentiation of bortezomib-induced lethal endoplasmic reticulum stress in mantle cell lymphoma cells.
Rao R, Nalluri S, Fiskus W, Savoie A, Buckley KM, Ha K, Balusu R, Joshi A, Coothankandaswamy V, Tao J, Sotomayor E, Atadja P, Bhalla KN. Rao R, et al. Among authors: buckley km. Clin Cancer Res. 2010 Oct 1;16(19):4742-54. doi: 10.1158/1078-0432.CCR-10-0529. Epub 2010 Jul 20. Clin Cancer Res. 2010. PMID: 20647473 Free PMC article.
Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists.
Mandawat A, Fiskus W, Buckley KM, Robbins K, Rao R, Balusu R, Navenot JM, Wang ZX, Ustun C, Chong DG, Atadja P, Fujii N, Peiper SC, Bhalla K. Mandawat A, et al. Among authors: buckley km. Blood. 2010 Dec 9;116(24):5306-15. doi: 10.1182/blood-2010-05-284414. Epub 2010 Sep 1. Blood. 2010. PMID: 20810927 Free article.
Activation of mTOR: A new mechanism "PIMed".
Buckley K, Fiskus W, Bhalla K. Buckley K, et al. Cancer Biol Ther. 2009 May;8(9):854-5. doi: 10.4161/cbt.8.9.8373. Epub 2009 May 9. Cancer Biol Ther. 2009. PMID: 19363296 Free article. No abstract available.
Editor's Note: Role of CAAT/Enhancer Binding Protein Homologous Protein in Panobinostat-mediated Potentiation of Bortezomib-induced Lethal Endoplasmic Reticulum Stress in Mantle Cell Lymphoma Cells.
Rao R, Nalluri S, Fiskus W, Savoie A, Buckley KM, Ha K, Balusu R, Joshi A, Coothankandaswamy V, Tao J, Sotomayor E, Atadja P, Bhalla KN. Rao R, et al. Among authors: buckley km. Clin Cancer Res. 2020 Mar 15;26(6):1531. doi: 10.1158/1078-0432.CCR-20-0412. Clin Cancer Res. 2020. PMID: 32169966 No abstract available.
Rapamycin up-regulation of autophagy reduces infarct size and improves outcomes in both permanent MCAL, and embolic MCAO, murine models of stroke.
Buckley KM, Hess DL, Sazonova IY, Periyasamy-Thandavan S, Barrett JR, Kirks R, Grace H, Kondrikova G, Johnson MH, Hess DC, Schoenlein PV, Hoda MN, Hill WD. Buckley KM, et al. Exp Transl Stroke Med. 2014 Jun 21;6:8. doi: 10.1186/2040-7378-6-8. eCollection 2014. Exp Transl Stroke Med. 2014. PMID: 24991402 Free PMC article.
High salt induces autocrine actions of ET-1 on inner medullary collecting duct NO production via upregulated ETB receptor expression.
Hyndman KA, Dugas C, Arguello AM, Goodchild TT, Buckley KM, Burch M, Yanagisawa M, Pollock JS. Hyndman KA, et al. Among authors: buckley km. Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R263-71. doi: 10.1152/ajpregu.00016.2015. Epub 2016 Jun 8. Am J Physiol Regul Integr Comp Physiol. 2016. PMID: 27280426 Free PMC article.
116 results