Shi Z - Search Results

1

Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene.

Shi Z, Dragin N, Gálvez-Peralta M, Jorge-Nebert LF, Miller ML, Wang B, Nebert DW. Shi Z, et al. Mol Pharmacol. 2010 Jul;78(1):46-57. doi: 10.1124/mol.110.063438. Epub 2010 Apr 6. Mol Pharmacol. 2010. PMID: 20371670 Free PMC article.

2

Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse.

Dragin N, Shi Z, Madan R, Karp CL, Sartor MA, Chen C, Gonzalez FJ, Nebert DW. Dragin N, et al. Among authors: shi z. Mol Pharmacol. 2008 Jun;73(6):1844-56. doi: 10.1124/mol.108.045658. Epub 2008 Mar 27. Mol Pharmacol. 2008. PMID: 18372398 Free PMC article.

3

Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle.

Dong H, Dalton TP, Miller ML, Chen Y, Uno S, Shi Z, Shertzer HG, Bansal S, Avadhani NG, Nebert DW. Dong H, et al. Among authors: shi z. Mol Pharmacol. 2009 Mar;75(3):555-67. doi: 10.1124/mol.108.051888. Epub 2008 Dec 1. Mol Pharmacol. 2009. PMID: 19047483 Free PMC article.

4

Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.

Shi Z, Dragin N, Miller ML, Stringer KF, Johansson E, Chen J, Uno S, Gonzalez FJ, Rubio CA, Nebert DW. Shi Z, et al. Int J Cancer. 2010 Nov 15;127(10):2334-50. doi: 10.1002/ijc.25222. Int J Cancer. 2010. PMID: 20127859 Free PMC article.

5

Oral benzo[a]pyrene in Cyp1a1/1b1(-/-) double-knockout mice: Microarray analysis during squamous cell carcinoma formation in preputial gland duct.

Gálvez-Peralta M, Shi Z, Chen J, Miller ML, Nebert DW. Gálvez-Peralta M, et al. Among authors: shi z. Int J Cancer. 2013 May 1;132(9):2065-75. doi: 10.1002/ijc.27897. Epub 2012 Dec 4. Int J Cancer. 2013. PMID: 23047765

6

Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm.

Nebert DW, Shi Z, Gálvez-Peralta M, Uno S, Dragin N. Nebert DW, et al. Among authors: shi z. Mol Pharmacol. 2013 Sep;84(3):304-13. doi: 10.1124/mol.113.086637. Epub 2013 Jun 12. Mol Pharmacol. 2013. PMID: 23761301 Free PMC article. Review.

7

Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.

Shi Z, Chen Y, Dong H, Amos-Kroohs RM, Nebert DW. Shi Z, et al. Biochem Biophys Res Commun. 2008 Nov 28;376(4):775-80. doi: 10.1016/j.bbrc.2008.09.068. Epub 2008 Sep 22. Biochem Biophys Res Commun. 2008. PMID: 18814841 Free PMC article.

8

Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.

Arlt VM, Levová K, Bárta F, Shi Z, Evans JD, Frei E, Schmeiser HH, Nebert DW, Phillips DH, Stiborová M. Arlt VM, et al. Among authors: shi z. Chem Res Toxicol. 2011 Oct 17;24(10):1710-9. doi: 10.1021/tx200259y. Epub 2011 Sep 29. Chem Res Toxicol. 2011. PMID: 21932800

9

Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.

Stiborová M, Levová K, Bárta F, Shi Z, Frei E, Schmeiser HH, Nebert DW, Phillips DH, Arlt VM. Stiborová M, et al. Among authors: shi z. Toxicol Sci. 2012 Feb;125(2):345-58. doi: 10.1093/toxsci/kfr306. Epub 2011 Nov 15. Toxicol Sci. 2012. PMID: 22086975 Free PMC article.

10

Inbreeding and epigenetics: beneficial as well as deleterious effects.

Nebert DW, Gálvez-Peralta M, Shi Z, Dragin N. Nebert DW, et al. Among authors: shi z. Nat Rev Genet. 2010 Sep;11(9):662. doi: 10.1038/nrg2664-c2. Epub 2010 Jul 27. Nat Rev Genet. 2010. PMID: 20661256 Free PMC article. No abstract available.

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