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Purified CDT toxins and a clean deletion within the CDT locus provide novel insights into the contribution of binary toxin in cellular inflammation and Clostridioides difficile infection.
Nabukhotna K, Kordus SL, Shupe JA, Cano Rodríguez R, Smith A, Bohannon JK, Washington MK, Lacy DB. Nabukhotna K, et al. Among authors: shupe ja. PLoS Pathog. 2024 Sep 19;20(9):e1012568. doi: 10.1371/journal.ppat.1012568. eCollection 2024 Sep. PLoS Pathog. 2024. PMID: 39298531 Free PMC article.
Inhibition of EGFR/ErbB does not protect against C. difficile toxin B.
Siddiqi U, Lunnemann HM, Childress KO, Shupe JA, Rutherford SA, Farrow MA, Washington MK, Coffey RJ, Lacy DB, Markham NO. Siddiqi U, et al. Among authors: shupe ja. bioRxiv [Preprint]. 2024 May 14:2024.05.13.594035. doi: 10.1101/2024.05.13.594035. bioRxiv. 2024. PMID: 38798529 Free PMC article. Preprint.
Increased intestinal permeability and downregulation of absorptive ion transporters Nhe3, Dra, and Sglt1 contribute to diarrhea during Clostridioides difficile infection.
Peritore-Galve FC, Kaji I, Smith A, Walker LM, Shupe JA, Washington MK, Algood HMS, Dudeja PK, Goldenring JR, Lacy DB. Peritore-Galve FC, et al. Among authors: shupe ja. Gut Microbes. 2023 Jan-Dec;15(1):2225841. doi: 10.1080/19490976.2023.2225841. Gut Microbes. 2023. PMID: 37350393 Free PMC article.
112 results