Moretti L - Search Results

1

AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer.

Moretti L, Li B, Kim KW, Chen H, Lu B. Moretti L, et al. J Thorac Oncol. 2010 May;5(5):680-7. doi: 10.1097/JTO.0b013e3181d6e08e. J Thorac Oncol. 2010. PMID: 20354451 Free article.

2

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.

Kim KW, Hwang M, Moretti L, Jaboin JJ, Cha YI, Lu B. Kim KW, et al. Among authors: moretti l. Autophagy. 2008 Jul;4(5):659-68. doi: 10.4161/auto.6058. Epub 2008 Apr 7. Autophagy. 2008. PMID: 18424912 Free PMC article.

3

M867, a novel selective inhibitor of caspase-3 enhances cell death and extends tumor growth delay in irradiated lung cancer models.

Kim KW, Moretti L, Lu B. Kim KW, et al. Among authors: moretti l. PLoS One. 2008 May 28;3(5):e2275. doi: 10.1371/journal.pone.0002275. PLoS One. 2008. PMID: 18509530 Free PMC article.

4

Radiosensitization of solid tumors by Z-VAD, a pan-caspase inhibitor.

Moretti L, Kim KW, Jung DK, Willey CD, Lu B. Moretti L, et al. Mol Cancer Ther. 2009 May;8(5):1270-9. doi: 10.1158/1535-7163.MCT-08-0893. Epub 2009 May 5. Mol Cancer Ther. 2009. PMID: 19417149 Free PMC article.

5

Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model.

Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B. Kim KW, et al. Among authors: moretti l. Clin Cancer Res. 2009 Oct 1;15(19):6096-105. doi: 10.1158/1078-0432.CCR-09-0589. Epub 2009 Sep 22. Clin Cancer Res. 2009. PMID: 19773376 Free PMC article.

6

Enzastaurin (LY317615), a protein kinase C beta selective inhibitor, enhances antiangiogenic effect of radiation.

Willey CD, Xiao D, Tu T, Kim KW, Moretti L, Niermann KJ, Tawtawy MN, Quarles CC, Lu B. Willey CD, et al. Among authors: moretti l. Int J Radiat Oncol Biol Phys. 2010 Aug 1;77(5):1518-26. doi: 10.1016/j.ijrobp.2009.06.044. Epub 2009 Nov 10. Int J Radiat Oncol Biol Phys. 2010. PMID: 19906497 Free PMC article.

7

Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models.

Sun Y, Moretti L, Giacalone NJ, Schleicher S, Speirs CK, Carbone DP, Lu B. Sun Y, et al. Among authors: moretti l. J Thorac Oncol. 2011 Apr;6(4):699-706. doi: 10.1097/JTO.0b013e31820d9d11. J Thorac Oncol. 2011. PMID: 21325979 Free PMC article.

8

MLN8054, a small molecule inhibitor of aurora kinase a, sensitizes androgen-resistant prostate cancer to radiation.

Moretti L, Niermann K, Schleicher S, Giacalone NJ, Varki V, Kim KW, Kopsombut P, Jung DK, Lu B. Moretti L, et al. Int J Radiat Oncol Biol Phys. 2011 Jul 15;80(4):1189-97. doi: 10.1016/j.ijrobp.2011.01.060. Epub 2011 Apr 20. Int J Radiat Oncol Biol Phys. 2011. PMID: 21514073

9

A novel bioluminescence orthotopic mouse model for advanced lung cancer.

Li B, Torossian A, Li W, Schleicher S, Niu K, Giacalone NJ, Kim SJ, Chen H, Gonzalez A, Moretti L, Lu B. Li B, et al. Among authors: moretti l. Radiat Res. 2011 Oct;176(4):486-93. doi: 10.1667/rr2565.1. Epub 2011 Jun 10. Radiat Res. 2011. PMID: 21663394 Free PMC article.

10

Endoplasmic reticulum stress mediates radiation-induced autophagy by perk-eIF2alpha in caspase-3/7-deficient cells.

Kim KW, Moretti L, Mitchell LR, Jung DK, Lu B. Kim KW, et al. Among authors: moretti l. Oncogene. 2010 Jun 3;29(22):3241-51. doi: 10.1038/onc.2010.74. Epub 2010 Mar 29. Oncogene. 2010. PMID: 20348950 Free PMC article.

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