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Some G protein heterotrimers physically dissociate in living cells.
Digby GJ, Lober RM, Sethi PR, Lambert NA. Digby GJ, et al. Among authors: lambert na. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17789-94. doi: 10.1073/pnas.0607116103. Epub 2006 Nov 9. Proc Natl Acad Sci U S A. 2006. PMID: 17095603 Free PMC article.
Differential dissociation of G protein heterotrimers.
Digby GJ, Sethi PR, Lambert NA. Digby GJ, et al. Among authors: lambert na. J Physiol. 2008 Jul 15;586(14):3325-35. doi: 10.1113/jphysiol.2008.153965. Epub 2008 May 22. J Physiol. 2008. PMID: 18499725 Free PMC article.
A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.
Willard FS, Zheng Z, Guo J, Digby GJ, Kimple AJ, Conley JM, Johnston CA, Bosch D, Willard MD, Watts VJ, Lambert NA, Ikeda SR, Du Q, Siderovski DP. Willard FS, et al. Among authors: lambert na. J Biol Chem. 2008 Dec 26;283(52):36698-710. doi: 10.1074/jbc.M804936200. Epub 2008 Nov 4. J Biol Chem. 2008. PMID: 18984596 Free PMC article.
GPCR dimers fall apart.
Lambert NA. Lambert NA. Sci Signal. 2010 Mar 30;3(115):pe12. doi: 10.1126/scisignal.3115pe12. Sci Signal. 2010. PMID: 20354223 Free PMC article.
Internalization dissociates β2-adrenergic receptors.
Lan TH, Kuravi S, Lambert NA. Lan TH, et al. Among authors: lambert na. PLoS One. 2011 Feb 22;6(2):e17361. doi: 10.1371/journal.pone.0017361. PLoS One. 2011. PMID: 21364942 Free PMC article.
111 results