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118 results

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Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)alpha1-specific activity and glucose transport in human skeletal muscle.
Deshmukh AS, Long YC, de Castro Barbosa T, Karlsson HK, Glund S, Zavadoski WJ, Gibbs EM, Koistinen HA, Wallberg-Henriksson H, Zierath JR. Deshmukh AS, et al. Among authors: gibbs em. Diabetologia. 2010 Jun;53(6):1142-50. doi: 10.1007/s00125-010-1716-x. Epub 2010 Mar 27. Diabetologia. 2010. PMID: 20349036 Free PMC article.
5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.
Wright SW, Rath VL, Genereux PE, Hageman DL, Levy CB, McClure LD, McCoid SC, McPherson RK, Schelhorn TM, Wilder DE, Zavadoski WJ, Gibbs EM, Treadway JL. Wright SW, et al. Among authors: gibbs em. Bioorg Med Chem Lett. 2005 Jan 17;15(2):459-65. doi: 10.1016/j.bmcl.2004.10.048. Bioorg Med Chem Lett. 2005. PMID: 15603973
Modeling the mechanism of action of a DGAT1 inhibitor using a causal reasoning platform.
Enayetallah AE, Ziemek D, Leininger MT, Randhawa R, Yang J, Manion TB, Mather DE, Zavadoski WJ, Kuhn M, Treadway JL, des Etages SA, Gibbs EM, Greene N, Steppan CM. Enayetallah AE, et al. Among authors: gibbs em. PLoS One. 2011;6(11):e27009. doi: 10.1371/journal.pone.0027009. Epub 2011 Nov 4. PLoS One. 2011. PMID: 22073239 Free PMC article.
Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1.
Dow RL, Li JC, Pence MP, Gibbs EM, LaPerle JL, Litchfield J, Piotrowski DW, Munchhof MJ, Manion TB, Zavadoski WJ, Walker GS, McPherson RK, Tapley S, Sugarman E, Guzman-Perez A, DaSilva-Jardine P. Dow RL, et al. Among authors: gibbs em. ACS Med Chem Lett. 2011 Mar 18;2(5):407-12. doi: 10.1021/ml200051p. eCollection 2011 May 12. ACS Med Chem Lett. 2011. PMID: 24900321 Free PMC article.
Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans.
Maciejewski BS, LaPerle JL, Chen D, Ghosh A, Zavadoski WJ, McDonald TS, Manion TB, Mather D, Patterson TA, Hanna M, Watkins S, Gibbs EM, Calle RA, Steppan CM. Maciejewski BS, et al. Among authors: gibbs em. Am J Physiol Gastrointest Liver Physiol. 2013 Jun 1;304(11):G958-69. doi: 10.1152/ajpgi.00384.2012. Epub 2013 Apr 4. Am J Physiol Gastrointest Liver Physiol. 2013. PMID: 23558010 Free article. Clinical Trial.
118 results