Ji H - Search Results

1

Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model.

Delker SL, Ji H, Li H, Jamal J, Fang J, Xue F, Silverman RB, Poulos TL. Delker SL, et al. Among authors: ji h. J Am Chem Soc. 2010 Apr 21;132(15):5437-42. doi: 10.1021/ja910228a. J Am Chem Soc. 2010. PMID: 20337441 Free PMC article.

2

Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.

Xue F, Huang J, Ji H, Fang J, Li H, Martásek P, Roman LJ, Poulos TL, Silverman RB. Xue F, et al. Among authors: ji h. Bioorg Med Chem. 2010 Sep 1;18(17):6526-37. doi: 10.1016/j.bmc.2010.06.074. Epub 2010 Jul 1. Bioorg Med Chem. 2010. PMID: 20673724 Free PMC article.

3

Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives.

Ji H, Delker SL, Li H, Martásek P, Roman LJ, Poulos TL, Silverman RB. Ji H, et al. J Med Chem. 2010 Nov 11;53(21):7804-24. doi: 10.1021/jm100947x. J Med Chem. 2010. PMID: 20958055 Free PMC article.

4

Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase.

Xue F, Kraus JM, Labby KJ, Ji H, Mataka J, Xia G, Li H, Delker SL, Roman LJ, Martásek P, Poulos TL, Silverman RB. Xue F, et al. Among authors: ji h. J Med Chem. 2011 Sep 22;54(18):6399-403. doi: 10.1021/jm200411j. Epub 2011 Aug 22. J Med Chem. 2011. PMID: 21809851 Free PMC article.

5

Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase.

Labby KJ, Xue F, Kraus JM, Ji H, Mataka J, Li H, Martásek P, Roman LJ, Poulos TL, Silverman RB. Labby KJ, et al. Among authors: ji h. Bioorg Med Chem. 2012 Apr 1;20(7):2435-43. doi: 10.1016/j.bmc.2012.01.037. Epub 2012 Feb 7. Bioorg Med Chem. 2012. PMID: 22370337 Free PMC article.

6

Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.

Huang H, Ji H, Li H, Jing Q, Labby KJ, Martásek P, Roman LJ, Poulos TL, Silverman RB. Huang H, et al. Among authors: ji h. J Am Chem Soc. 2012 Jul 18;134(28):11559-72. doi: 10.1021/ja302269r. Epub 2012 Jul 10. J Am Chem Soc. 2012. PMID: 22731813 Free PMC article.

7

Targeting nitric oxide signaling with nNOS inhibitors as a novel strategy for the therapy and prevention of human melanoma.

Yang Z, Misner B, Ji H, Poulos TL, Silverman RB, Meyskens FL, Yang S. Yang Z, et al. Among authors: ji h. Antioxid Redox Signal. 2013 Aug 10;19(5):433-47. doi: 10.1089/ars.2012.4563. Epub 2013 Jan 18. Antioxid Redox Signal. 2013. PMID: 23199242 Free PMC article.

8

Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase.

Li H, Xue F, Kraus JM 2nd, Ji H, Labby KJ, Mataka J, Delker SL, Martásek P, Roman LJ, Poulos TL, Silverman RB. Li H, et al. Among authors: ji h. Bioorg Med Chem. 2013 Mar 1;21(5):1333-43. doi: 10.1016/j.bmc.2012.12.019. Epub 2012 Dec 22. Bioorg Med Chem. 2013. PMID: 23352768 Free PMC article.

9

The mobility of a conserved tyrosine residue controls isoform-dependent enzyme-inhibitor interactions in nitric oxide synthases.

Li H, Jamal J, Delker S, Plaza C, Ji H, Jing Q, Huang H, Kang S, Silverman RB, Poulos TL. Li H, et al. Among authors: ji h. Biochemistry. 2014 Aug 19;53(32):5272-9. doi: 10.1021/bi500561h. Epub 2014 Aug 11. Biochemistry. 2014. PMID: 25089924 Free PMC article.

10

Hydroxyl-terminated peptidomimetic inhibitors of neuronal nitric oxide synthase.

Mbadugha BN, Seo J, Ji H, Martásek P, Roman LJ, Shea TM, Li H, Poulos TL, Silverman RB. Mbadugha BN, et al. Among authors: ji h. Bioorg Med Chem. 2006 Jun 1;14(11):3681-90. doi: 10.1016/j.bmc.2006.01.044. Epub 2006 Feb 9. Bioorg Med Chem. 2006. PMID: 16480878

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