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Pre-clinical properties of the alpha4beta2 nicotinic acetylcholine receptor partial agonists varenicline, cytisine and dianicline translate to clinical efficacy for nicotine dependence.
Rollema H, Shrikhande A, Ward KM, Tingley FD 3rd, Coe JW, O'Neill BT, Tseng E, Wang EQ, Mather RJ, Hurst RS, Williams KE, de Vries M, Cremers T, Bertrand S, Bertrand D. Rollema H, et al. Among authors: bertrand s, bertrand d. Br J Pharmacol. 2010 May;160(2):334-45. doi: 10.1111/j.1476-5381.2010.00682.x. Epub 2010 Mar 22. Br J Pharmacol. 2010. PMID: 20331614 Free PMC article.
Steroids inhibit nicotinic acetylcholine receptors.
Bertrand D, Valera S, Bertrand S, Ballivet M, Rungger D. Bertrand D, et al. Among authors: bertrand s. Neuroreport. 1991 May;2(5):277-80. doi: 10.1097/00001756-199105000-00016. Neuroreport. 1991. PMID: 1717043
539 results