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The phosphatase and tensin homolog regulates epidermal growth factor receptor (EGFR) inhibitor response by targeting EGFR for degradation.
Vivanco I, Rohle D, Versele M, Iwanami A, Kuga D, Oldrini B, Tanaka K, Dang J, Kubek S, Palaskas N, Hsueh T, Evans M, Mulholland D, Wolle D, Rajasekaran S, Rajasekaran A, Liau LM, Cloughesy TF, Dikic I, Brennan C, Wu H, Mischel PS, Perera T, Mellinghoff IK. Vivanco I, et al. Among authors: versele m. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6459-64. doi: 10.1073/pnas.0911188107. Epub 2010 Mar 22. Proc Natl Acad Sci U S A. 2010. PMID: 20308550 Free PMC article.
Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib.
Woyach JA, Furman RR, Liu TM, Ozer HG, Zapatka M, Ruppert AS, Xue L, Li DH, Steggerda SM, Versele M, Dave SS, Zhang J, Yilmaz AS, Jaglowski SM, Blum KA, Lozanski A, Lozanski G, James DF, Barrientos JC, Lichter P, Stilgenbauer S, Buggy JJ, Chang BY, Johnson AJ, Byrd JC. Woyach JA, et al. Among authors: versele m. N Engl J Med. 2014 Jun 12;370(24):2286-94. doi: 10.1056/NEJMoa1400029. Epub 2014 May 28. N Engl J Med. 2014. PMID: 24869598 Free PMC article.
Novel mechanisms in nutrient activation of the yeast protein kinase A pathway.
Thevelein JM, Bonini BM, Castermans D, Haesendonckx S, Kriel J, Louwet W, Thayumanavan P, Popova Y, Rubio-Texeira M, Schepers W, Vandormael P, Van Zeebroeck G, Verhaert P, Versele M, Voordeckers K. Thevelein JM, et al. Among authors: versele m. Acta Microbiol Immunol Hung. 2008 Jun;55(2):75-89. doi: 10.1556/AMicr.55.2008.2.1. Acta Microbiol Immunol Hung. 2008. PMID: 18595314 Review.
Yeast 3-phosphoinositide-dependent protein kinase-1 (PDK1) orthologs Pkh1-3 differentially regulate phosphorylation of protein kinase A (PKA) and the protein kinase B (PKB)/S6K ortholog Sch9.
Voordeckers K, Kimpe M, Haesendonckx S, Louwet W, Versele M, Thevelein JM. Voordeckers K, et al. Among authors: versele m. J Biol Chem. 2011 Jun 24;286(25):22017-27. doi: 10.1074/jbc.M110.200071. Epub 2011 Apr 29. J Biol Chem. 2011. PMID: 21531713 Free PMC article.
33 results