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Combinations of mutations in the connection domain of human immunodeficiency virus type 1 reverse transcriptase: assessing the impact on nucleoside and nonnucleoside reverse transcriptase inhibitor resistance.
Gupta S, Fransen S, Paxinos EE, Stawiski E, Huang W, Petropoulos CJ. Gupta S, et al. Among authors: fransen s. Antimicrob Agents Chemother. 2010 May;54(5):1973-80. doi: 10.1128/AAC.00870-09. Epub 2010 Mar 1. Antimicrob Agents Chemother. 2010. PMID: 20194692 Free PMC article.
Multiple genetic pathways involving amino acid position 143 of HIV-1 integrase are preferentially associated with specific secondary amino acid substitutions and confer resistance to raltegravir and cross-resistance to elvitegravir.
Huang W, Frantzell A, Fransen S, Petropoulos CJ. Huang W, et al. Among authors: fransen s. Antimicrob Agents Chemother. 2013 Sep;57(9):4105-13. doi: 10.1128/AAC.00204-13. Epub 2013 Jun 3. Antimicrob Agents Chemother. 2013. PMID: 23733474 Free PMC article.
Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals.
Huang W, Toma J, Stawiski E, Fransen S, Wrin T, Parkin N, Whitcomb JM, Coakley E, Hecht FM, Deeks SG, Gandhi RT, Eshleman SH, Petropoulos CJ. Huang W, et al. Among authors: fransen s. AIDS Res Hum Retroviruses. 2009 Aug;25(8):795-802. doi: 10.1089/aid.2008.0252. AIDS Res Hum Retroviruses. 2009. PMID: 19678765 Free PMC article.
Connection domain mutations in HIV-1 reverse transcriptase do not impact etravirine susceptibility and virologic responses to etravirine-containing regimens.
Gupta S, Vingerhoets J, Fransen S, Tambuyzer L, Azijn H, Frantzell A, Paredes R, Coakley E, Nijs S, Clotet B, Petropoulos CJ, Schapiro J, Huang W, Picchio G. Gupta S, et al. Among authors: fransen s. Antimicrob Agents Chemother. 2011 Jun;55(6):2872-9. doi: 10.1128/AAC.01695-10. Epub 2011 Apr 4. Antimicrob Agents Chemother. 2011. PMID: 21464253 Free PMC article.
Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism.
Whitcomb JM, Huang W, Fransen S, Limoli K, Toma J, Wrin T, Chappey C, Kiss LD, Paxinos EE, Petropoulos CJ. Whitcomb JM, et al. Among authors: fransen s. Antimicrob Agents Chemother. 2007 Feb;51(2):566-75. doi: 10.1128/AAC.00853-06. Epub 2006 Nov 20. Antimicrob Agents Chemother. 2007. PMID: 17116663 Free PMC article.
121 results