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CVID-associated TACI mutations affect autoreactive B cell selection and activation.
Romberg N, Chamberlain N, Saadoun D, Gentile M, Kinnunen T, Ng YS, Virdee M, Menard L, Cantaert T, Morbach H, Rachid R, Martinez-Pomar N, Matamoros N, Geha R, Grimbacher B, Cerutti A, Cunningham-Rundles C, Meffre E. Romberg N, et al. Among authors: menard l. J Clin Invest. 2013 Oct;123(10):4283-93. doi: 10.1172/JCI69854. Epub 2013 Sep 24. J Clin Invest. 2013. PMID: 24051380 Free PMC article.
Decreased somatic hypermutation induces an impaired peripheral B cell tolerance checkpoint.
Cantaert T, Schickel JN, Bannock JM, Ng YS, Massad C, Delmotte FR, Yamakawa N, Glauzy S, Chamberlain N, Kinnunen T, Menard L, Lavoie A, Walter JE, Notarangelo LD, Bruneau J, Al-Herz W, Kilic SS, Ochs HD, Cunningham-Rundles C, van der Burg M, Kuijpers TW, Kracker S, Kaneko H, Sekinaka Y, Nonoyama S, Durandy A, Meffre E. Cantaert T, et al. Among authors: menard l. J Clin Invest. 2016 Nov 1;126(11):4289-4302. doi: 10.1172/JCI84645. Epub 2016 Oct 4. J Clin Invest. 2016. PMID: 27701145 Free PMC article.
Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells.
Janssen E, Morbach H, Ullas S, Bannock JM, Massad C, Menard L, Barlan I, Lefranc G, Su H, Dasouki M, Al-Herz W, Keles S, Chatila T, Geha RS, Meffre E. Janssen E, et al. Among authors: menard l. J Allergy Clin Immunol. 2014 Dec;134(6):1365-1374. doi: 10.1016/j.jaci.2014.07.042. Epub 2014 Sep 11. J Allergy Clin Immunol. 2014. PMID: 25218284 Free PMC article.
Positive and negative selection shape the human naive B cell repertoire.
Chen JW, Schickel JN, Tsakiris N, Sng J, Arbogast F, Bouis D, Parisi D, Gera R, Boeckers JM, Delmotte FR, Veselits M, Schuetz C, Jacobsen EM, Posovszky C, Schulz AS, Schwarz K, Clark MR, Menard L, Meffre E. Chen JW, et al. Among authors: menard l. J Clin Invest. 2022 Jan 18;132(2):e150985. doi: 10.1172/JCI150985. J Clin Invest. 2022. PMID: 34813502 Free PMC article.
Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens.
Young RM, Wu T, Schmitz R, Dawood M, Xiao W, Phelan JD, Xu W, Menard L, Meffre E, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza LM, Staudt LM. Young RM, et al. Among authors: menard l. Proc Natl Acad Sci U S A. 2015 Nov 3;112(44):13447-54. doi: 10.1073/pnas.1514944112. Epub 2015 Oct 19. Proc Natl Acad Sci U S A. 2015. PMID: 26483459 Free PMC article.
230 results