Shi Y - Search Results

1

Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment.

Kidd S, Caldwell L, Dietrich M, Samudio I, Spaeth EL, Watson K, Shi Y, Abbruzzese J, Konopleva M, Andreeff M, Marini FC. Kidd S, et al. Among authors: shi y. Cytotherapy. 2010 Sep;12(5):615-25. doi: 10.3109/14653241003631815. Cytotherapy. 2010. PMID: 20230221

2

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

Zeng Z, Shi YX, Samudio IJ, Wang RY, Ling X, Frolova O, Levis M, Rubin JB, Negrin RR, Estey EH, Konoplev S, Andreeff M, Konopleva M. Zeng Z, et al. Blood. 2009 Jun 11;113(24):6215-24. doi: 10.1182/blood-2008-05-158311. Epub 2008 Oct 27. Blood. 2009. PMID: 18955566 Free PMC article.

3

Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.

Konopleva M, Shi Y, Steelman LS, Shelton JG, Munsell M, Marini F, McQueen T, Contractor R, McCubrey JA, Andreeff M. Konopleva M, et al. Among authors: shi y. Cancer Res. 2005 Nov 1;65(21):9962-70. doi: 10.1158/0008-5472.CAN-05-1068. Cancer Res. 2005. PMID: 16267021

4

Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells.

Battula VL, Evans KW, Hollier BG, Shi Y, Marini FC, Ayyanan A, Wang RY, Brisken C, Guerra R, Andreeff M, Mani SA. Battula VL, et al. Among authors: shi y. Stem Cells. 2010 Aug;28(8):1435-45. doi: 10.1002/stem.467. Stem Cells. 2010. PMID: 20572012 Free PMC article.

5

Mesenchymal Stem Cells Overexpressing IFN-β Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model.

Ling X, Marini F, Konopleva M, Schober W, Shi Y, Burks J, Clise-Dwyer K, Wang RY, Zhang W, Yuan X, Lu H, Caldwell L, Andreeff M. Ling X, et al. Among authors: shi y. Cancer Microenviron. 2010 Mar 19;3(1):83-95. doi: 10.1007/s12307-010-0041-8. Cancer Microenviron. 2010. PMID: 21209776 Free PMC article.

6

Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis.

Battula VL, Shi Y, Evans KW, Wang RY, Spaeth EL, Jacamo RO, Guerra R, Sahin AA, Marini FC, Hortobagyi G, Mani SA, Andreeff M. Battula VL, et al. Among authors: shi y. J Clin Invest. 2012 Jun;122(6):2066-78. doi: 10.1172/JCI59735. Epub 2012 May 15. J Clin Invest. 2012. PMID: 22585577 Free PMC article. Clinical Trial.

7

The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo.

Ling X, Spaeth E, Chen Y, Shi Y, Zhang W, Schober W, Hail N Jr, Konopleva M, Andreeff M. Ling X, et al. Among authors: shi y. PLoS One. 2013;8(3):e58426. doi: 10.1371/journal.pone.0058426. Epub 2013 Mar 6. PLoS One. 2013. PMID: 23484027 Free PMC article.

8

Targeting connective tissue growth factor (CTGF) in acute lymphoblastic leukemia preclinical models: anti-CTGF monoclonal antibody attenuates leukemia growth.

Lu H, Kojima K, Battula VL, Korchin B, Shi Y, Chen Y, Spong S, Thomas DA, Kantarjian H, Lock RB, Andreeff M, Konopleva M. Lu H, et al. Among authors: shi y. Ann Hematol. 2014 Mar;93(3):485-492. doi: 10.1007/s00277-013-1939-2. Epub 2013 Oct 24. Ann Hematol. 2014. PMID: 24154679 Free PMC article.

9

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.

Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo PP, Kitada S, Deng X, Zhai D, Shi YX, Sneed T, Verhaegen M, Soengas M, Ruvolo VR, McQueen T, Schober WD, Watt JC, Jiffar T, Ling X, Marini FC, Harris D, Dietrich M, Estrov Z, McCubrey J, May WS, Reed JC, Andreeff M. Konopleva M, et al. Cancer Cell. 2006 Nov;10(5):375-88. doi: 10.1016/j.ccr.2006.10.006. Cancer Cell. 2006. PMID: 17097560 Free article.

10

Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment.

Zeng Z, Shi YX, Tsao T, Qiu Y, Kornblau SM, Baggerly KA, Liu W, Jessen K, Liu Y, Kantarjian H, Rommel C, Fruman DA, Andreeff M, Konopleva M. Zeng Z, et al. Among authors: shi yx. Blood. 2012 Sep 27;120(13):2679-89. doi: 10.1182/blood-2011-11-393934. Epub 2012 Jul 23. Blood. 2012. PMID: 22826565 Free PMC article.

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