Oka S - Search Results

1

DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1.

Martin SA, McCabe N, Mullarkey M, Cummins R, Burgess DJ, Nakabeppu Y, Oka S, Kay E, Lord CJ, Ashworth A. Martin SA, et al. Among authors: oka s. Cancer Cell. 2010 Mar 16;17(3):235-48. doi: 10.1016/j.ccr.2009.12.046. Cancer Cell. 2010. PMID: 20227038 Free PMC article.

2

DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis.

Oka S, Nakabeppu Y. Oka S, et al. Cancer Sci. 2011 Apr;102(4):677-82. doi: 10.1111/j.1349-7006.2011.01869.x. Epub 2011 Feb 17. Cancer Sci. 2011. PMID: 21235684 Free article. Review.

3

Construction and characterization of a cell line deficient in repair of mitochondrial, but not nuclear, oxidative DNA damage.

Oka S, Ohno M, Nakabeppu Y. Oka S, et al. Methods Mol Biol. 2009;554:251-64. doi: 10.1007/978-1-59745-521-3_16. Methods Mol Biol. 2009. PMID: 19513679

4

Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method.

Ohno M, Oka S, Nakabeppu Y. Ohno M, et al. Among authors: oka s. Methods Mol Biol. 2009;554:199-212. doi: 10.1007/978-1-59745-521-3_13. Methods Mol Biol. 2009. PMID: 19513676

5

8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.

Sheng Z, Oka S, Tsuchimoto D, Abolhassani N, Nomaru H, Sakumi K, Yamada H, Nakabeppu Y. Sheng Z, et al. Among authors: oka s. J Clin Invest. 2012 Dec;122(12):4344-61. doi: 10.1172/JCI65053. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143307 Free PMC article.

6

Two distinct pathways of cell death triggered by oxidative damage to nuclear and mitochondrial DNAs.

Oka S, Ohno M, Tsuchimoto D, Sakumi K, Furuichi M, Nakabeppu Y. Oka S, et al. EMBO J. 2008 Jan 23;27(2):421-32. doi: 10.1038/sj.emboj.7601975. Epub 2008 Jan 10. EMBO J. 2008. PMID: 18188152 Free PMC article.

7

Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain.

Abolhassani N, Leon J, Sheng Z, Oka S, Hamasaki H, Iwaki T, Nakabeppu Y. Abolhassani N, et al. Among authors: oka s. Mech Ageing Dev. 2017 Jan;161(Pt A):95-104. doi: 10.1016/j.mad.2016.05.005. Epub 2016 May 24. Mech Ageing Dev. 2017. PMID: 27233446 Review.

8

Role of the DNA repair glycosylase OGG1 in the activation of murine splenocytes.

Seifermann M, Ulges A, Bopp T, Melcea S, Schäfer A, Oka S, Nakabeppu Y, Klungland A, Niehrs C, Epe B. Seifermann M, et al. Among authors: oka s. DNA Repair (Amst). 2017 Oct;58:13-20. doi: 10.1016/j.dnarep.2017.08.005. Epub 2017 Aug 12. DNA Repair (Amst). 2017. PMID: 28843610

9

Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death.

Ichikawa J, Tsuchimoto D, Oka S, Ohno M, Furuichi M, Sakumi K, Nakabeppu Y. Ichikawa J, et al. Among authors: oka s. DNA Repair (Amst). 2008 Mar 1;7(3):418-30. doi: 10.1016/j.dnarep.2007.11.007. Epub 2007 Dec 21. DNA Repair (Amst). 2008. PMID: 18155646

10

8-Oxoguanine accumulation in mitochondrial DNA causes mitochondrial dysfunction and impairs neuritogenesis in cultured adult mouse cortical neurons under oxidative conditions.

Leon J, Sakumi K, Castillo E, Sheng Z, Oka S, Nakabeppu Y. Leon J, et al. Among authors: oka s. Sci Rep. 2016 Feb 25;6:22086. doi: 10.1038/srep22086. Sci Rep. 2016. PMID: 26912170 Free PMC article.

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