The hypersensitivity of the Chinese hamster ovary variant BL-10 to bleomycin killing is due to a lack of glutathione S-transferase-alpha activity.
Giaccia AJ, Lewis AD, Denko NC, Cholon A, Evans JW, Waldren CA, Stamato TD, Brown JM.
Giaccia AJ, et al.
Cancer Res. 1991 Aug 15;51(16):4463-9.
Cancer Res. 1991.
PMID: 1714344
Peters, P. Patil, N. Denko, R. Weinstein, and A. Giaccia. Cancer Res., 47: 1588-1592, 1987). One class of mutants represented by the cell line BL-10 displays only hypersensitivity to killing by bleomycin in both acute (16 h) and chronic treatments but no sensitivity …
Peters, P. Patil, N. Denko, R. Weinstein, and A. Giaccia. Cancer Res., 47: 1588-1592, 1987). One class of mutants represented …