Pelkonen O - Search Results

1

Rapid screening of commercially available herbal products for the inhibition of major human hepatic cytochrome P450 enzymes using the N-in-one cocktail.

Sevior DK, Hokkanen J, Tolonen A, Abass K, Tursas L, Pelkonen O, Ahokas JT. Sevior DK, et al. Among authors: pelkonen o. Xenobiotica. 2010 Apr;40(4):245-54. doi: 10.3109/00498251003592683. Xenobiotica. 2010. PMID: 20218935

2

Metabolism of α-thujone in human hepatic preparations in vitro.

Abass K, Reponen P, Mattila S, Pelkonen O. Abass K, et al. Among authors: pelkonen o. Xenobiotica. 2011 Feb;41(2):101-11. doi: 10.3109/00498254.2010.528066. Epub 2010 Nov 18. Xenobiotica. 2011. PMID: 21087116

3

The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: comparison of the N-in-one and single substrate approaches.

Abass K, Pelkonen O. Abass K, et al. Among authors: pelkonen o. Toxicol In Vitro. 2013 Aug;27(5):1584-8. doi: 10.1016/j.tiv.2012.05.003. Epub 2012 May 23. Toxicol In Vitro. 2013. PMID: 22634058

4

Predictive value of animal models for human cytochrome P450 (CYP)-mediated metabolism: a comparative study in vitro.

Turpeinen M, Ghiciuc C, Opritoui M, Tursas L, Pelkonen O, Pasanen M. Turpeinen M, et al. Among authors: pelkonen o. Xenobiotica. 2007 Dec;37(12):1367-77. doi: 10.1080/00498250701658312. Xenobiotica. 2007. PMID: 17943662

5

An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes.

Abass K, Turpeinen M, Pelkonen O. Abass K, et al. Among authors: pelkonen o. J Environ Sci Health B. 2009 Aug;44(6):553-63. doi: 10.1080/03601230902997766. J Environ Sci Health B. 2009. PMID: 20183062

6

Metabolism of carbosulfan II. Human interindividual variability in its in vitro hepatic biotransformation and the identification of the cytochrome P450 isoforms involved.

Abass K, Reponen P, Mattila S, Pelkonen O. Abass K, et al. Among authors: pelkonen o. Chem Biol Interact. 2010 May 14;185(3):163-73. doi: 10.1016/j.cbi.2010.03.024. Epub 2010 Mar 20. Chem Biol Interact. 2010. PMID: 20307514

7

Metabolism of dexfenfluramine in human liver microsomes and by recombinant enzymes: role of CYP2D6 and 1A2.

Haritos VS, Ching MS, Ghabrial H, Gross AS, Taavitsainen P, Pelkonen O, Battaglia SE, Smallwood RA, Ahokas JT. Haritos VS, et al. Among authors: pelkonen o. Pharmacogenetics. 1998 Oct;8(5):423-32. doi: 10.1097/00008571-199810000-00007. Pharmacogenetics. 1998. PMID: 9825834

8

Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes.

Abass K, Reponen P, Turpeinen M, Jalonen J, Pelkonen O. Abass K, et al. Among authors: pelkonen o. Drug Metab Dispos. 2007 Sep;35(9):1634-41. doi: 10.1124/dmd.107.016295. Epub 2007 Jun 18. Drug Metab Dispos. 2007. PMID: 17576805

9

Functional expression, inhibition and induction of CYP enzymes in HepaRG cells.

Turpeinen M, Tolonen A, Chesne C, Guillouzo A, Uusitalo J, Pelkonen O. Turpeinen M, et al. Among authors: pelkonen o. Toxicol In Vitro. 2009 Jun;23(4):748-53. doi: 10.1016/j.tiv.2009.03.008. Epub 2009 Mar 26. Toxicol In Vitro. 2009. PMID: 19328226

10

Cytochrome P450 (CYP) inhibition screening: comparison of three tests.

Turpeinen M, Korhonen LE, Tolonen A, Uusitalo J, Juvonen R, Raunio H, Pelkonen O. Turpeinen M, et al. Among authors: pelkonen o. Eur J Pharm Sci. 2006 Oct 1;29(2):130-8. doi: 10.1016/j.ejps.2006.06.005. Epub 2006 Jun 27. Eur J Pharm Sci. 2006. PMID: 16890411

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