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Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes.
Sanmarco LM, Wheeler MA, Gutiérrez-Vázquez C, Polonio CM, Linnerbauer M, Pinho-Ribeiro FA, Li Z, Giovannoni F, Batterman KV, Scalisi G, Zandee SEJ, Heck ES, Alsuwailm M, Rosene DL, Becher B, Chiu IM, Prat A, Quintana FJ. Sanmarco LM, et al. Nature. 2021 Feb;590(7846):473-479. doi: 10.1038/s41586-020-03116-4. Epub 2021 Jan 6. Nature. 2021. PMID: 33408417 Free PMC article.
Pain and infection: pathogen detection by nociceptors.
Chiu IM, Pinho-Ribeiro FA, Woolf CJ. Chiu IM, et al. Pain. 2016 Jun;157(6):1192-1193. doi: 10.1097/j.pain.0000000000000559. Pain. 2016. PMID: 27183444 Free PMC article. No abstract available.
Nociceptor nerves set the stage for skin immunity.
Pinho-Ribeiro FA, Chiu IM. Pinho-Ribeiro FA, et al. Cell Res. 2019 Nov;29(11):877-878. doi: 10.1038/s41422-019-0240-x. Cell Res. 2019. PMID: 31619764 Free PMC article. No abstract available.
The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.
Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK. Wallrapp A, et al. Nature. 2017 Sep 21;549(7672):351-356. doi: 10.1038/nature24029. Epub 2017 Sep 13. Nature. 2017. PMID: 28902842 Free PMC article.
Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense.
Lai NY, Musser MA, Pinho-Ribeiro FA, Baral P, Jacobson A, Ma P, Potts DE, Chen Z, Paik D, Soualhi S, Yan Y, Misra A, Goldstein K, Lagomarsino VN, Nordstrom A, Sivanathan KN, Wallrapp A, Kuchroo VK, Nowarski R, Starnbach MN, Shi H, Surana NK, An D, Wu C, Huh JR, Rao M, Chiu IM. Lai NY, et al. Cell. 2020 Jan 9;180(1):33-49.e22. doi: 10.1016/j.cell.2019.11.014. Epub 2019 Dec 5. Cell. 2020. PMID: 31813624 Free PMC article.
634 results