Sicheri F - Search Results

1

Allosteric protein kinase regulation by pseudokinases: insights from STRAD.

Rajakulendran T, Sicheri F. Rajakulendran T, et al. Among authors: sicheri f. Sci Signal. 2010 Mar 2;3(111):pe8. doi: 10.1126/scisignal.3111pe8. Sci Signal. 2010. PMID: 20197543 Review.

2

Molecular glues that inhibit deubiquitylase activity and inflammatory signalling.

Chandler F, Reddy PAN, Bhutda S, Ross RL, Datta A, Walden M, Walker K, Di Donato S, Cassel JA, Prakesch MA, Aman A, Datti A, Campbell LJ, Foglizzo M, Bell L, Stein DN, Ault JR, Al-Awar RS, Calabrese AN, Sicheri F, Del Galdo F, Salvino JM, Greenberg RA, Zeqiraj E. Chandler F, et al. Among authors: sicheri f. bioRxiv [Preprint]. 2024 Nov 15:2024.09.07.611787. doi: 10.1101/2024.09.07.611787. bioRxiv. 2024. PMID: 39282282 Free PMC article. Preprint.

3

A polo match for Plk1.

Leung GC, Sicheri F. Leung GC, et al. Among authors: sicheri f. Cell. 2003 Oct 3;115(1):3-4. doi: 10.1016/s0092-8674(03)00761-x. Cell. 2003. PMID: 14531994 Free article.

4

Higher-order substrate recognition of eIF2alpha by the RNA-dependent protein kinase PKR.

Dar AC, Dever TE, Sicheri F. Dar AC, et al. Among authors: sicheri f. Cell. 2005 Sep 23;122(6):887-900. doi: 10.1016/j.cell.2005.06.044. Cell. 2005. PMID: 16179258 Free article.

5

Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain.

Murphy JM, Korzhnev DM, Ceccarelli DF, Briant DJ, Zarrine-Afsar A, Sicheri F, Kay LE, Pawson T. Murphy JM, et al. Among authors: sicheri f. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14336-41. doi: 10.1073/pnas.0703012104. Epub 2007 Aug 28. Proc Natl Acad Sci U S A. 2007. PMID: 17726107 Free PMC article.

6

Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing.

Lee KP, Dey M, Neculai D, Cao C, Dever TE, Sicheri F. Lee KP, et al. Among authors: sicheri f. Cell. 2008 Jan 11;132(1):89-100. doi: 10.1016/j.cell.2007.10.057. Cell. 2008. PMID: 18191223 Free PMC article.

7

CNK and HYP form a discrete dimer by their SAM domains to mediate RAF kinase signaling.

Rajakulendran T, Sahmi M, Kurinov I, Tyers M, Therrien M, Sicheri F. Rajakulendran T, et al. Among authors: sicheri f. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2836-41. doi: 10.1073/pnas.0709705105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287031 Free PMC article.

8

A dimerization-dependent mechanism drives RAF catalytic activation.

Rajakulendran T, Sahmi M, Lefrançois M, Sicheri F, Therrien M. Rajakulendran T, et al. Among authors: sicheri f. Nature. 2009 Sep 24;461(7263):542-5. doi: 10.1038/nature08314. Epub 2009 Sep 2. Nature. 2009. PMID: 19727074

9

An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase.

Orlicky S, Tang X, Neduva V, Elowe N, Brown ED, Sicheri F, Tyers M. Orlicky S, et al. Among authors: sicheri f. Nat Biotechnol. 2010 Jul;28(7):733-7. doi: 10.1038/nbt.1646. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581844 Free PMC article.

10

Mechanistic principles of RAF kinase signaling.

Udell CM, Rajakulendran T, Sicheri F, Therrien M. Udell CM, et al. Among authors: sicheri f. Cell Mol Life Sci. 2011 Feb;68(4):553-65. doi: 10.1007/s00018-010-0520-6. Epub 2010 Sep 6. Cell Mol Life Sci. 2011. PMID: 20820846 Free PMC article. Review.

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