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Page 1
Metabolism in T cell activation and differentiation.
Pearce EL. Pearce EL. Curr Opin Immunol. 2010 Jun;22(3):314-20. doi: 10.1016/j.coi.2010.01.018. Epub 2010 Feb 26. Curr Opin Immunol. 2010. PMID: 20189791 Free PMC article. Review.
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.
Everts B, Amiel E, Huang SC, Smith AM, Chang CH, Lam WY, Redmann V, Freitas TC, Blagih J, van der Windt GJ, Artyomov MN, Jones RG, Pearce EL, Pearce EJ. Everts B, et al. Among authors: pearce ej, pearce el. Nat Immunol. 2014 Apr;15(4):323-32. doi: 10.1038/ni.2833. Epub 2014 Feb 23. Nat Immunol. 2014. PMID: 24562310 Free PMC article.
Autophagy is essential for effector CD8(+) T cell survival and memory formation.
Xu X, Araki K, Li S, Han JH, Ye L, Tan WG, Konieczny BT, Bruinsma MW, Martinez J, Pearce EL, Green DR, Jones DP, Virgin HW, Ahmed R. Xu X, et al. Among authors: pearce el. Nat Immunol. 2014 Dec;15(12):1152-61. doi: 10.1038/ni.3025. Epub 2014 Nov 2. Nat Immunol. 2014. PMID: 25362489 Free PMC article.
Targeting T cell metabolism for therapy.
O'Sullivan D, Pearce EL. O'Sullivan D, et al. Among authors: pearce el. Trends Immunol. 2015 Feb;36(2):71-80. doi: 10.1016/j.it.2014.12.004. Epub 2015 Jan 15. Trends Immunol. 2015. PMID: 25601541 Free PMC article. Review.
T cell metabolism drives immunity.
Buck MD, O'Sullivan D, Pearce EL. Buck MD, et al. Among authors: pearce el. J Exp Med. 2015 Aug 24;212(9):1345-60. doi: 10.1084/jem.20151159. Epub 2015 Aug 10. J Exp Med. 2015. PMID: 26261266 Free PMC article. Review.
131 results