Cooper J - Search Results

1

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.

Li W, You L, Cooper J, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Li W, et al. Among authors: cooper j. Cell. 2010 Feb 19;140(4):477-90. doi: 10.1016/j.cell.2010.01.029. Cell. 2010. PMID: 20178741 Free PMC article.

2

Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression.

Cooper J, Li W, You L, Schiavon G, Pepe-Caprio A, Zhou L, Ishii R, Giovannini M, Hanemann CO, Long SB, Erdjument-Bromage H, Zhou P, Tempst P, Giancotti FG. Cooper J, et al. Sci Signal. 2011 Aug 23;4(188):pt6. doi: 10.1126/scisignal.2002314. Sci Signal. 2011. PMID: 21878678

3

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.

Li W, Cooper J, Karajannis MA, Giancotti FG. Li W, et al. Among authors: cooper j. EMBO Rep. 2012 Mar;13(3):204-15. doi: 10.1038/embor.2012.11. EMBO Rep. 2012. PMID: 22482125 Free PMC article. Review.

4

Molecular insights into NF2/Merlin tumor suppressor function.

Cooper J, Giancotti FG. Cooper J, et al. FEBS Lett. 2014 Aug 19;588(16):2743-52. doi: 10.1016/j.febslet.2014.04.001. Epub 2014 Apr 12. FEBS Lett. 2014. PMID: 24726726 Free PMC article. Review.

5

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus.

Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO, Zhou P, Karajannis MA, Giancotti FG. Li W, et al. Among authors: cooper j. Cancer Cell. 2014 Jul 14;26(1):48-60. doi: 10.1016/j.ccr.2014.05.001. Cancer Cell. 2014. PMID: 25026211 Free PMC article.

6

Cancer: a new role for non-canonical Hippo signaling.

Cooper J, Giancotti FG. Cooper J, et al. Cell Res. 2017 Apr;27(4):459-460. doi: 10.1038/cr.2017.27. Epub 2017 Feb 28. Cell Res. 2017. PMID: 28244491 Free PMC article.

7

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss-Driven Tumorigenesis.

Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG. Cooper J, et al. Mol Cancer Ther. 2017 Aug;16(8):1693-1704. doi: 10.1158/1535-7163.MCT-16-0821. Epub 2017 May 3. Mol Cancer Ther. 2017. PMID: 28468780 Free PMC article.

8

Integrin Signaling in Cancer: Mechanotransduction, Stemness, Epithelial Plasticity, and Therapeutic Resistance.

Cooper J, Giancotti FG. Cooper J, et al. Cancer Cell. 2019 Mar 18;35(3):347-367. doi: 10.1016/j.ccell.2019.01.007. Cancer Cell. 2019. PMID: 30889378 Free PMC article. Review.

9

Correction: Combined Inhibition of NEDD8-activating Enzyme and mTOR Suppresses NF2 Loss-driven Tumorigenesis.

Cooper J, Xu Q, Zhou L, Pavlovic M, Ojeda V, Moulick K, de Stanchina E, Poirier JT, Zauderer M, Rudin CM, Karajannis MA, Hanemann CO, Giancotti FG. Cooper J, et al. Mol Cancer Ther. 2021 Feb;20(2):450. doi: 10.1158/1535-7163.MCT-20-1027. Mol Cancer Ther. 2021. PMID: 33547247 No abstract available.

10

Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer.

Zaman A, Wu X, Lemoff A, Yadavalli S, Lee J, Wang C, Cooper J, McMillan EA, Yeaman C, Mirzaei H, White MA, Bivona TG. Zaman A, et al. Among authors: cooper j. Cell Rep. 2021 Aug 3;36(5):109491. doi: 10.1016/j.celrep.2021.109491. Cell Rep. 2021. PMID: 34348154 Free PMC article.

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