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Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation.
Scruggs SB, Hinken AC, Thawornkaiwong A, Robbins J, Walker LA, de Tombe PP, Geenen DL, Buttrick PM, Solaro RJ. Scruggs SB, et al. Among authors: hinken ac. J Biol Chem. 2009 Feb 20;284(8):5097-106. doi: 10.1074/jbc.M807414200. Epub 2008 Dec 23. J Biol Chem. 2009. PMID: 19106098 Free PMC article.
Desensitization of myofilaments to Ca2+ as a therapeutic target for hypertrophic cardiomyopathy with mutations in thin filament proteins.
Alves ML, Dias FAL, Gaffin RD, Simon JN, Montminy EM, Biesiadecki BJ, Hinken AC, Warren CM, Utter MS, Davis RT Rd, Sakthivel S, Robbins J, Wieczorek DF, Solaro RJ, Wolska BM. Alves ML, et al. Among authors: hinken ac. Circ Cardiovasc Genet. 2014 Apr;7(2):132-143. doi: 10.1161/CIRCGENETICS.113.000324. Epub 2014 Feb 28. Circ Cardiovasc Genet. 2014. PMID: 24585742 Free PMC article.
28 results