An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before
sharing sensitive information, make sure you’re on a federal
government site.
The site is secure.
The https:// ensures that you are connecting to the
official website and that any information you provide is encrypted
and transmitted securely.
Kales A, Manfredi RL, Vgontzas AN, Bixler EO, Vela-Bueno A, Fee EC.Kales A, et al. Among authors: manfredi rl.Clin Pharmacol Ther. 1991 Apr;49(4):468-76. doi: 10.1038/clpt.1991.55.Clin Pharmacol Ther. 1991.PMID: 2015735Clinical Trial.
Kales A, Bixler EO, Vela-Bueno A, Soldatos CR, Niklaus DE, Manfredi RL.Kales A, et al. Among authors: manfredi rl.Clin Pharmacol Ther. 1986 Oct;40(4):378-86. doi: 10.1038/clpt.1986.194.Clin Pharmacol Ther. 1986.PMID: 3530586Clinical Trial.