Harrington KJ - Search Results

1

Assessment of the Na/I symporter as a reporter gene to visualize oncolytic adenovirus propagation in peritoneal tumours.

Merron A, Baril P, Martin-Duque P, de la Vieja A, Tran L, Briat A, Harrington KJ, McNeish IA, Vassaux G. Merron A, et al. Among authors: harrington kj. Eur J Nucl Med Mol Imaging. 2010 Jul;37(7):1377-85. doi: 10.1007/s00259-009-1379-3. Epub 2010 Feb 6. Eur J Nucl Med Mol Imaging. 2010. PMID: 20140612

2

A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor.

Hu JC, Coffin RS, Davis CJ, Graham NJ, Groves N, Guest PJ, Harrington KJ, James ND, Love CA, McNeish I, Medley LC, Michael A, Nutting CM, Pandha HS, Shorrock CA, Simpson J, Steiner J, Steven NM, Wright D, Coombes RC. Hu JC, et al. Among authors: harrington kj. Clin Cancer Res. 2006 Nov 15;12(22):6737-47. doi: 10.1158/1078-0432.CCR-06-0759. Clin Cancer Res. 2006. PMID: 17121894 Clinical Trial.

3

SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene.

Merron A, Peerlinck I, Martin-Duque P, Burnet J, Quintanilla M, Mather S, Hingorani M, Harrington K, Iggo R, Vassaux G. Merron A, et al. Gene Ther. 2007 Dec;14(24):1731-8. doi: 10.1038/sj.gt.3303043. Epub 2007 Oct 25. Gene Ther. 2007. PMID: 17960161

4

Radiation-mediated up-regulation of gene expression from replication-defective adenoviral vectors: implications for sodium iodide symporter gene therapy.

Hingorani M, White CL, Zaidi S, Merron A, Peerlinck I, Gore ME, Nutting CM, Pandha HS, Melcher AA, Vile RG, Vassaux G, Harrington KJ. Hingorani M, et al. Among authors: harrington kj. Clin Cancer Res. 2008 Aug 1;14(15):4915-24. doi: 10.1158/1078-0432.CCR-07-4049. Clin Cancer Res. 2008. PMID: 18676766

5

Exploiting synergies between radiation and oncolytic viruses.

Harrington KJ, Melcher A, Vassaux G, Pandha HS, Vile RG. Harrington KJ, et al. Curr Opin Mol Ther. 2008 Aug;10(4):362-70. Curr Opin Mol Ther. 2008. PMID: 18683101 Review.

6

Inhibition of repair of radiation-induced DNA damage enhances gene expression from replication-defective adenoviral vectors.

Hingorani M, White CL, Merron A, Peerlinck I, Gore ME, Slade A, Scott SD, Nutting CM, Pandha HS, Melcher AA, Vile RG, Vassaux G, Harrington KJ. Hingorani M, et al. Among authors: harrington kj. Cancer Res. 2008 Dec 1;68(23):9771-8. doi: 10.1158/0008-5472.CAN-08-1911. Cancer Res. 2008. PMID: 19047156

7

Therapeutic effect of sodium iodide symporter gene therapy combined with external beam radiotherapy and targeted drugs that inhibit DNA repair.

Hingorani M, White CL, Zaidi S, Pandha HS, Melcher AA, Bhide SA, Nutting CM, Syrigos KN, Vile RG, Vassaux G, Harrington KJ. Hingorani M, et al. Among authors: harrington kj. Mol Ther. 2010 Sep;18(9):1599-605. doi: 10.1038/mt.2010.120. Epub 2010 Jun 29. Mol Ther. 2010. PMID: 20588260 Free PMC article.

8

Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck.

Harrington KJ, Hingorani M, Tanay MA, Hickey J, Bhide SA, Clarke PM, Renouf LC, Thway K, Sibtain A, McNeish IA, Newbold KL, Goldsweig H, Coffin R, Nutting CM. Harrington KJ, et al. Clin Cancer Res. 2010 Aug 1;16(15):4005-15. doi: 10.1158/1078-0432.CCR-10-0196. Clin Cancer Res. 2010. PMID: 20670951 Free article. Clinical Trial.

9

Review article: gene therapy, recent developments and future prospects in gastrointestinal oncology.

Touchefeu Y, Harrington KJ, Galmiche JP, Vassaux G. Touchefeu Y, et al. Among authors: harrington kj. Aliment Pharmacol Ther. 2010 Oct;32(8):953-68. doi: 10.1111/j.1365-2036.2010.04424.x. Epub 2010 Aug 15. Aliment Pharmacol Ther. 2010. PMID: 20937041 Free article. Review.

10

The use of molecular imaging of gene expression by radiotracers in gene therapy.

Richard-Fiardo P, Franken PR, Harrington KJ, Vassaux G, Cambien B. Richard-Fiardo P, et al. Among authors: harrington kj. Expert Opin Biol Ther. 2011 Oct;11(10):1273-85. doi: 10.1517/14712598.2011.588596. Epub 2011 Jun 2. Expert Opin Biol Ther. 2011. PMID: 21635148 Review.

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