Sasaki Y - Search Results

1

Novel multiple opioid ligands based on 4-aminobenzazepinone (Aba), azepinoindole (Aia) and tetrahydroisoquinoline (Tic) scaffolds.

Ballet S, Marczak ED, Feytens D, Salvadori S, Sasaki Y, Abell AD, Lazarus LH, Balboni G, Tourwé D. Ballet S, et al. Among authors: sasaki y. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1610-3. doi: 10.1016/j.bmcl.2010.01.055. Epub 2010 Jan 20. Bioorg Med Chem Lett. 2010. PMID: 20137938 Free PMC article.

2

Endomorphin 2 analogues containing Dmp residue as an aromatic amino acid surrogate with high mu-opioid receptor affinity and selectivity.

Sasaki Y, Sasaki A, Niizuma H, Goto H, Ambo A. Sasaki Y, et al. Among authors: sasaki a. Bioorg Med Chem. 2003 Mar 6;11(5):675-8. doi: 10.1016/s0968-0896(02)00601-6. Bioorg Med Chem. 2003. PMID: 12537996

3

Structural studies of [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bond.

Okada Y, Fujita Y, Motoyama T, Tsuda Y, Yokoi T, Li T, Sasaki Y, Ambo A, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: sasaki y. Bioorg Med Chem. 2003 May 1;11(9):1983-94. doi: 10.1016/s0968-0896(03)00068-3. Bioorg Med Chem. 2003. PMID: 12670649

4

Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesia.

Okada Y, Tsuda Y, Fujita Y, Yokoi T, Sasaki Y, Ambo A, Konishi R, Nagata M, Salvadori S, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: sasaki y. J Med Chem. 2003 Jul 17;46(15):3201-9. doi: 10.1021/jm020459z. J Med Chem. 2003. PMID: 12852751

5

Novel 2',6'-dimethyl-L-tyrosine-containing pyrazinone opioid mimetic mu-agonists with potent antinociceptive activity in mice.

Jinsmaa Y, Okada Y, Tsuda Y, Shiotani K, Sasaki Y, Ambo A, Bryant SD, Lazarus LH. Jinsmaa Y, et al. Among authors: sasaki y. J Pharmacol Exp Ther. 2004 Apr;309(1):432-8. doi: 10.1124/jpet.103.060061. Epub 2004 Jan 12. J Pharmacol Exp Ther. 2004. PMID: 14718580

6

Oral bioavailability of a new class of micro-opioid receptor agonists containing 3,6-bis[Dmt-NH(CH(2))(n)]-2(1H)-pyrazinone with central-mediated analgesia.

Jinsmaa Y, Miyazaki A, Fujita Y, Li T, Fujisawa Y, Shiotani K, Tsuda Y, Yokoi T, Ambo A, Sasaki Y, Bryant SD, Lazarus LH, Okada Y. Jinsmaa Y, et al. Among authors: sasaki y. J Med Chem. 2004 May 6;47(10):2599-610. doi: 10.1021/jm0304616. J Med Chem. 2004. PMID: 15115401

7

Development of potent bifunctional endomorphin-2 analogues with mixed mu-/delta-opioid agonist and delta-opioid antagonist properties.

Fujita Y, Tsuda Y, Li T, Motoyama T, Takahashi M, Shimizu Y, Yokoi T, Sasaki Y, Ambo A, Kita A, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Fujita Y, et al. Among authors: sasaki y. J Med Chem. 2004 Jul 1;47(14):3591-9. doi: 10.1021/jm030649p. J Med Chem. 2004. PMID: 15214786

8

Development of potent mu-opioid receptor ligands using unique tyrosine analogues of endomorphin-2.

Li T, Fujita Y, Tsuda Y, Miyazaki A, Ambo A, Sasaki Y, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Li T, et al. Among authors: sasaki y. J Med Chem. 2005 Jan 27;48(2):586-92. doi: 10.1021/jm049384k. J Med Chem. 2005. PMID: 15658871

9

Studies on the structure-activity relationship of 2',6'-dimethyl-l-tyrosine (Dmt) derivatives: bioactivity profile of H-Dmt-NH-CH(3).

Fujita Y, Tsuda Y, Motoyama T, Li T, Miyazaki A, Yokoi T, Sasaki Y, Ambo A, Niizuma H, Jinsmaa Y, Bryant SD, Lazarus LH, Okada Y. Fujita Y, et al. Among authors: sasaki y. Bioorg Med Chem Lett. 2005 Feb 1;15(3):599-602. doi: 10.1016/j.bmcl.2004.11.040. Bioorg Med Chem Lett. 2005. PMID: 15664820

10

Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouse.

Jinsmaa Y, Fujita Y, Shiotani K, Miyazaki A, Li T, Tsuda Y, Okada Y, Ambo A, Sasaki Y, Bryant SD, Lazarus LH. Jinsmaa Y, et al. Among authors: sasaki y. Eur J Pharmacol. 2005 Feb 10;509(1):37-42. doi: 10.1016/j.ejphar.2004.12.015. Epub 2005 Jan 22. Eur J Pharmacol. 2005. PMID: 15713427

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

6,164 results

Search Page

Filters