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Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic.
Balboni G, Fiorini S, Baldisserotto A, Trapella C, Sasaki Y, Ambo A, Marczak ED, Lazarus LH, Salvadori S. Balboni G, et al. Among authors: marczak ed. J Med Chem. 2008 Aug 28;51(16):5109-17. doi: 10.1021/jm800587e. Epub 2008 Aug 5. J Med Chem. 2008. PMID: 18680274 Free PMC article.
Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold.
Ballet S, Feytens D, Wachter RD, Vlaeminck MD, Marczak ED, Salvadori S, Graaf Cd, Rognan D, Negri L, Lattanzi R, Lazarus LH, Tourwé D, Balboni G. Ballet S, et al. Among authors: marczak ed. Bioorg Med Chem Lett. 2009 Jan 15;19(2):433-7. doi: 10.1016/j.bmcl.2008.11.051. Epub 2008 Nov 19. Bioorg Med Chem Lett. 2009. PMID: 19062273 Free PMC article.
Role of 2',6'-dimethyl-l-tyrosine (Dmt) in some opioid lead compounds.
Balboni G, Marzola E, Sasaki Y, Ambo A, Marczak ED, Lazarus LH, Salvadori S. Balboni G, et al. Among authors: marczak ed. Bioorg Med Chem. 2010 Aug 15;18(16):6024-30. doi: 10.1016/j.bmc.2010.06.073. Epub 2010 Jun 25. Bioorg Med Chem. 2010. PMID: 20637637 Free PMC article.
Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic.
Balboni G, Salvadori S, Marczak ED, Knapp BI, Bidlack JM, Lazarus LH, Peng X, Si YG, Neumeyer JL. Balboni G, et al. Among authors: marczak ed. Eur J Med Chem. 2011 Feb;46(2):799-803. doi: 10.1016/j.ejmech.2010.12.001. Epub 2010 Dec 8. Eur J Med Chem. 2011. PMID: 21216504 Free PMC article.
24 results