Lakshmanan V - Search Results

1

A non-radioactive DAPI-based high-throughput in vitro assay to assess Plasmodium falciparum responsiveness to antimalarials--increased sensitivity of P. falciparum to chloroquine in Senegal.

Ndiaye D, Patel V, Demas A, LeRoux M, Ndir O, Mboup S, Clardy J, Lakshmanan V, Daily JP, Wirth DF. Ndiaye D, et al. Among authors: lakshmanan v. Am J Trop Med Hyg. 2010 Feb;82(2):228-30. doi: 10.4269/ajtmh.2010.09-0470. Am J Trop Med Hyg. 2010. PMID: 20133997 Free PMC article.

2

Plasmodium falciparum biology: analysis of in vitro versus in vivo growth conditions.

LeRoux M, Lakshmanan V, Daily JP. LeRoux M, et al. Among authors: lakshmanan v. Trends Parasitol. 2009 Oct;25(10):474-81. doi: 10.1016/j.pt.2009.07.005. Epub 2009 Sep 9. Trends Parasitol. 2009. PMID: 19747879 Review.

3

Metabolomic analysis of patient plasma yields evidence of plant-like α-linolenic acid metabolism in Plasmodium falciparum.

Lakshmanan V, Rhee KY, Wang W, Yu Y, Khafizov K, Fiser A, Wu P, Ndir O, Mboup S, Ndiaye D, Daily JP. Lakshmanan V, et al. J Infect Dis. 2012 Jul 15;206(2):238-48. doi: 10.1093/infdis/jis339. Epub 2012 May 7. J Infect Dis. 2012. PMID: 22566569 Free PMC article.

4

Metabolomics and malaria biology.

Lakshmanan V, Rhee KY, Daily JP. Lakshmanan V, et al. Mol Biochem Parasitol. 2011 Feb;175(2):104-11. doi: 10.1016/j.molbiopara.2010.09.008. Epub 2010 Oct 21. Mol Biochem Parasitol. 2011. PMID: 20970461 Free PMC article. Review.

5

Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes.

Ecker A, Lakshmanan V, Sinnis P, Coppens I, Fidock DA. Ecker A, et al. Among authors: lakshmanan v. J Infect Dis. 2011 Jan 15;203(2):228-36. doi: 10.1093/infdis/jiq036. J Infect Dis. 2011. PMID: 21288823 Free PMC article.

6

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance.

Lakshmanan V, Bray PG, Verdier-Pinard D, Johnson DJ, Horrocks P, Muhle RA, Alakpa GE, Hughes RH, Ward SA, Krogstad DJ, Sidhu AB, Fidock DA. Lakshmanan V, et al. EMBO J. 2005 Jul 6;24(13):2294-305. doi: 10.1038/sj.emboj.7600681. Epub 2005 Jun 9. EMBO J. 2005. PMID: 15944738 Free PMC article.

7

Chloroquine-resistant isoforms of the Plasmodium falciparum chloroquine resistance transporter acidify lysosomal pH in HEK293 cells more than chloroquine-sensitive isoforms.

Reeves DC, Liebelt DA, Lakshmanan V, Roepe PD, Fidock DA, Akabas MH. Reeves DC, et al. Among authors: lakshmanan v. Mol Biochem Parasitol. 2006 Dec;150(2):288-99. doi: 10.1016/j.molbiopara.2006.09.001. Epub 2006 Sep 25. Mol Biochem Parasitol. 2006. PMID: 17014918 Free PMC article.

8

A transgenic Plasmodium falciparum NF54 strain that expresses GFP-luciferase throughout the parasite life cycle.

Vaughan AM, Mikolajczak SA, Camargo N, Lakshmanan V, Kennedy M, Lindner SE, Miller JL, Hume JC, Kappe SH. Vaughan AM, et al. Among authors: lakshmanan v. Mol Biochem Parasitol. 2012 Dec;186(2):143-7. doi: 10.1016/j.molbiopara.2012.10.004. Epub 2012 Oct 27. Mol Biochem Parasitol. 2012. PMID: 23107927

9

A next-generation genetically attenuated Plasmodium falciparum parasite created by triple gene deletion.

Mikolajczak SA, Lakshmanan V, Fishbaugher M, Camargo N, Harupa A, Kaushansky A, Douglass AN, Baldwin M, Healer J, O'Neill M, Phuong T, Cowman A, Kappe SH. Mikolajczak SA, et al. Among authors: lakshmanan v. Mol Ther. 2014 Sep;22(9):1707-15. doi: 10.1038/mt.2014.85. Epub 2014 May 14. Mol Ther. 2014. PMID: 24827907 Free PMC article.

10

Evidence for a central role for PfCRT in conferring Plasmodium falciparum resistance to diverse antimalarial agents.

Johnson DJ, Fidock DA, Mungthin M, Lakshmanan V, Sidhu AB, Bray PG, Ward SA. Johnson DJ, et al. Among authors: lakshmanan v. Mol Cell. 2004 Sep 24;15(6):867-77. doi: 10.1016/j.molcel.2004.09.012. Mol Cell. 2004. PMID: 15383277 Free PMC article.

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