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A fast, single-vesicle fusion assay mimics physiological SNARE requirements.
Karatekin E, Di Giovanni J, Iborra C, Coleman J, O'Shaughnessy B, Seagar M, Rothman JE. Karatekin E, et al. Among authors: rothman je. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3517-21. doi: 10.1073/pnas.0914723107. Epub 2010 Feb 2. Proc Natl Acad Sci U S A. 2010. PMID: 20133592 Free PMC article.
Entropic forces drive self-organization and membrane fusion by SNARE proteins.
Mostafavi H, Thiyagarajan S, Stratton BS, Karatekin E, Warner JM, Rothman JE, O'Shaughnessy B. Mostafavi H, et al. Among authors: rothman je. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5455-5460. doi: 10.1073/pnas.1611506114. Epub 2017 May 10. Proc Natl Acad Sci U S A. 2017. PMID: 28490503 Free PMC article.
Nascent fusion pore opening monitored at single-SNAREpin resolution.
Heo P, Coleman J, Fleury JB, Rothman JE, Pincet F. Heo P, et al. Among authors: rothman je. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2024922118. doi: 10.1073/pnas.2024922118. Proc Natl Acad Sci U S A. 2021. PMID: 33495324 Free PMC article.
Calcium sensitive ring-like oligomers formed by synaptotagmin.
Wang J, Bello O, Auclair SM, Wang J, Coleman J, Pincet F, Krishnakumar SS, Sindelar CV, Rothman JE. Wang J, et al. Among authors: rothman je. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13966-71. doi: 10.1073/pnas.1415849111. Epub 2014 Sep 8. Proc Natl Acad Sci U S A. 2014. PMID: 25201968 Free PMC article.
Protein determinants of SNARE-mediated lipid mixing.
Ji H, Coleman J, Yang R, Melia TJ, Rothman JE, Tareste D. Ji H, et al. Among authors: rothman je. Biophys J. 2010 Jul 21;99(2):553-60. doi: 10.1016/j.bpj.2010.04.060. Biophys J. 2010. PMID: 20643074 Free PMC article.
329 results