Zacuto M - Search Results

1

Asymmetric synthesis of a potent, aminopiperidine-fused imidazopyridine dipeptidyl peptidase IV inhibitor.

Xu F, Corley E, Zacuto M, Conlon DA, Pipik B, Humphrey G, Murry J, Tschaen D. Xu F, et al. Among authors: zacuto m. J Org Chem. 2010 Mar 5;75(5):1343-53. doi: 10.1021/jo902573q. J Org Chem. 2010. PMID: 20128619

2

Asymmetric synthesis of telcagepant, a CGRP receptor antagonist for the treatment of migraine.

Xu F, Zacuto M, Yoshikawa N, Desmond R, Hoerrner S, Itoh T, Journet M, Humphrey GR, Cowden C, Strotman N, Devine P. Xu F, et al. Among authors: zacuto m. J Org Chem. 2010 Nov 19;75(22):7829-41. doi: 10.1021/jo101704b. Epub 2010 Oct 18. J Org Chem. 2010. PMID: 20954694

3

One-step RhCl3-catalyzed deprotection of acyclic N-allyl amides.

Zacuto MJ, Xu F. Zacuto MJ, et al. J Org Chem. 2007 Aug 3;72(16):6298-300. doi: 10.1021/jo070553t. Epub 2007 Jul 11. J Org Chem. 2007. PMID: 17625881

4

Asymmetric synthesis of highly functionalized tetrahydropyran DPP-4 inhibitor.

Xu F, Zacuto MJ, Kohmura Y, Rosen J, Gibb A, Alam M, Scott J, Tschaen D. Xu F, et al. Among authors: zacuto mj. Org Lett. 2014 Oct 17;16(20):5422-5. doi: 10.1021/ol502661g. Epub 2014 Sep 30. Org Lett. 2014. PMID: 25269068

5

Chemoselectivity of the Ru-catalyzed cycloisomerization reaction for the synthesis of dihydropyrans; application to the synthesis of L-forosamine.

Zacuto MJ, Tomita D, Pirzada Z, Xu F. Zacuto MJ, et al. Org Lett. 2010 Feb 19;12(4):684-7. doi: 10.1021/ol9026667. Org Lett. 2010. PMID: 20088537

6

Synthesis of the HCV protease inhibitor Vaniprevir (MK-7009) using ring-closing metathesis strategy.

Kong J, Chen CY, Balsells-Padros J, Cao Y, Dunn RF, Dolman SJ, Janey J, Li H, Zacuto MJ. Kong J, et al. Among authors: zacuto mj. J Org Chem. 2012 Apr 20;77(8):3820-8. doi: 10.1021/jo3001595. Epub 2012 Apr 10. J Org Chem. 2012. PMID: 22458448

7

One-step synthesis of 1-chloro-3-arylacetone derivatives from arylacetic acids.

Zacuto MJ, Dunn RF, Figus M. Zacuto MJ, et al. J Org Chem. 2014 Sep 19;79(18):8917-25. doi: 10.1021/jo5016486. Epub 2014 Sep 3. J Org Chem. 2014. PMID: 25184954

8

Synthesis of Acrylamides via the Doebner-Knoevenagel Condensation.

Zacuto MJ. Zacuto MJ. J Org Chem. 2019 May 17;84(10):6465-6474. doi: 10.1021/acs.joc.9b00450. Epub 2019 Apr 29. J Org Chem. 2019. PMID: 30997800

9

Tandem silylformylation-crotylsilylation/Tamao oxidation of internal alkynes: a remarkable example of generating complexity from simplicity.

Spletstoser JT, Zacuto MJ, Leighton JL. Spletstoser JT, et al. Among authors: zacuto mj. Org Lett. 2008 Dec 18;10(24):5593-6. doi: 10.1021/ol802489w. Org Lett. 2008. PMID: 19007175 Free PMC article.

10

Nickel/Photoredox-Catalyzed Methylation of (Hetero)aryl Chlorides Using Trimethyl Orthoformate as a Methyl Radical Source.

Kariofillis SK, Shields BJ, Tekle-Smith MA, Zacuto MJ, Doyle AG. Kariofillis SK, et al. Among authors: zacuto mj. J Am Chem Soc. 2020 Apr 22;142(16):7683-7689. doi: 10.1021/jacs.0c02805. Epub 2020 Apr 10. J Am Chem Soc. 2020. PMID: 32275411 Free PMC article.

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