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CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.
Klatt NR, Shudo E, Ortiz AM, Engram JC, Paiardini M, Lawson B, Miller MD, Else J, Pandrea I, Estes JD, Apetrei C, Schmitz JE, Ribeiro RM, Perelson AS, Silvestri G. Klatt NR, et al. Among authors: else j. PLoS Pathog. 2010 Jan 29;6(1):e1000747. doi: 10.1371/journal.ppat.1000747. PLoS Pathog. 2010. PMID: 20126441 Free PMC article.
Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
Klatt NR, Villinger F, Bostik P, Gordon SN, Pereira L, Engram JC, Mayne A, Dunham RM, Lawson B, Ratcliffe SJ, Sodora DL, Else J, Reimann K, Staprans SI, Haase AT, Estes JD, Silvestri G, Ansari AA. Klatt NR, et al. Among authors: else j. J Clin Invest. 2008 Jun;118(6):2039-49. doi: 10.1172/JCI33814. J Clin Invest. 2008. PMID: 18497876 Free PMC article.
A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo.
Riddick NE, Hermann EA, Loftin LM, Elliott ST, Wey WC, Cervasi B, Taaffe J, Engram JC, Li B, Else JG, Li Y, Hahn BH, Derdeyn CA, Sodora DL, Apetrei C, Paiardini M, Silvestri G, Collman RG. Riddick NE, et al. Among authors: else jg. PLoS Pathog. 2010 Aug 26;6(8):e1001064. doi: 10.1371/journal.ppat.1001064. PLoS Pathog. 2010. PMID: 20865163 Free PMC article.
Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21.
Pallikkuth S, Micci L, Ende ZS, Iriele RI, Cervasi B, Lawson B, McGary CS, Rogers KA, Else JG, Silvestri G, Easley K, Estes JD, Villinger F, Pahwa S, Paiardini M. Pallikkuth S, et al. Among authors: else jg. PLoS Pathog. 2013;9(7):e1003471. doi: 10.1371/journal.ppat.1003471. Epub 2013 Jul 4. PLoS Pathog. 2013. PMID: 23853592 Free PMC article.
A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation.
Taaffe J, Chahroudi A, Engram J, Sumpter B, Meeker T, Ratcliffe S, Paiardini M, Else J, Silvestri G. Taaffe J, et al. Among authors: else j. J Virol. 2010 Jun;84(11):5476-84. doi: 10.1128/JVI.00039-10. Epub 2010 Mar 24. J Virol. 2010. PMID: 20335252 Free PMC article.
Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression.
Paiardini M, Cervasi B, Reyes-Aviles E, Micci L, Ortiz AM, Chahroudi A, Vinton C, Gordon SN, Bosinger SE, Francella N, Hallberg PL, Cramer E, Schlub T, Chan ML, Riddick NE, Collman RG, Apetrei C, Pandrea I, Else J, Munch J, Kirchhoff F, Davenport MP, Brenchley JM, Silvestri G. Paiardini M, et al. Among authors: else j. Nat Med. 2011 Jun 26;17(7):830-6. doi: 10.1038/nm.2395. Nat Med. 2011. PMID: 21706028 Free PMC article.
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
Ortiz AM, Klatt NR, Li B, Yi Y, Tabb B, Hao XP, Sternberg L, Lawson B, Carnathan PM, Cramer EM, Engram JC, Little DM, Ryzhova E, Gonzalez-Scarano F, Paiardini M, Ansari AA, Ratcliffe S, Else JG, Brenchley JM, Collman RG, Estes JD, Derdeyn CA, Silvestri G. Ortiz AM, et al. J Clin Invest. 2011 Nov;121(11):4433-45. doi: 10.1172/JCI46023. Epub 2011 Oct 17. J Clin Invest. 2011. PMID: 22005304 Free PMC article.
97 results