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A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.
Krokowski D, Han J, Saikia M, Majumder M, Yuan CL, Guan BJ, Bevilacqua E, Bussolati O, Bröer S, Arvan P, Tchórzewski M, Snider MD, Puchowicz M, Croniger CM, Kimball SR, Pan T, Koromilas AE, Kaufman RJ, Hatzoglou M. Krokowski D, et al. Among authors: puchowicz m. J Biol Chem. 2013 Jun 14;288(24):17202-13. doi: 10.1074/jbc.M113.466920. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645676 Free PMC article.
Oxidative metabolism: glucose versus ketones.
Prince A, Zhang Y, Croniger C, Puchowicz M. Prince A, et al. Among authors: puchowicz m. Adv Exp Med Biol. 2013;789:323-328. doi: 10.1007/978-1-4614-7411-1_43. Adv Exp Med Biol. 2013. PMID: 23852511
Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice.
Cordoba-Chacon J, Majumdar N, List EO, Diaz-Ruiz A, Frank SJ, Manzano A, Bartrons R, Puchowicz M, Kopchick JJ, Kineman RD. Cordoba-Chacon J, et al. Among authors: puchowicz m. Diabetes. 2015 Sep;64(9):3093-103. doi: 10.2337/db15-0370. Epub 2015 May 26. Diabetes. 2015. PMID: 26015548 Free PMC article.
98 results